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Rabbit Anti-FVT1/FITC Conjugated antibody (bs-13233R-FITC)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13233R-FITC
英文名稱 Rabbit Anti-FVT1/FITC Conjugated antibody
中文名稱 FITC標記的濾泡型轉運蛋白1/II型慢性淋巴性白血病抗體
別    名 3 dehydrosphinganine reductase; 3 ketodihydrosphingosine reductase; 3-dehydrosphinganine reductase; 3-ketodihydrosphingosine reductase; DHSR; FLJ36555; FLJ92680; Follicular lymphoma variant translocation 1; Follicular variant translocation protein 1; FVT 1; FVT-1; FVT1; KDS reductase; KDSR; KDSR_HUMAN; SDR35C1; Short chain dehydrogenase/reductase family 35C member 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  轉運蛋白  細胞類型標志物  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FVT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).

Function:
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes.

DISEASE:
Note=A chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Database links:
UniProtKB/Swiss-Prot: Q06136.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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