超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲日韩中文在线精品第一,最新国产在线视频,亚洲国产精品久
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FYCO1/Gold Conjugated antibody (bs-13237R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-13237R-Gold
英文名稱 Rabbit Anti-FYCO1/Gold Conjugated antibody
中文名稱 膠體金標記的鋅指蛋白FYCO1抗體
別    名 DKFZp779K1152; FLJ13335; FYCO1; FYCO1_HUMAN; FYVE and coiled coil domain containing 1; FYVE and coiled coil domain containing protein 1; FYVE and coiled-coil domain-containing protein 1; MGC126517; MGC126519; RUFY3; RUN and FYVE domain containing 3; Zinc finger FYVE domain-containing protein 7.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 167kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FYCO1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
FYCO1 is a 1,478 amino acid protein that contains one RUN domain, one GOLD domain and one FYVE-type zinc finger. Expressed in heart and skeletal muscle, FYCO1 exists as multiple alternatively spliced isoforms and may play a role in transcriptional regulation events. In response to DNA damage, FYCO1 is subject to phosphorylation, probably by ATM or ATR. The gene encoding FYCO1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Function:
May mediate microtubule plus end-directed vesicle transport.

Subunit:
Can form homodimers. Interacts (via C-terminus) with MAP1LC3B. Interacts with RAB7A; the interaction with RAB7A induces FYCO1 recruitment to late endosomal/lysosomal compartments.

Subcellular Location:
Cytoplasmic vesicle, autophagosome. Endosome. Lysosome. Note=Localizes to the external but not to the internal membrane of autophagosomes, and upon autophagosome/late endosome/lysosome fusion, it stays on the external surface of autolysosomes.

Tissue Specificity:
Expressed in heart and skeletal muscle.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

DISEASE:
Defects in FYCO1 are the cause of cataract congenital autosomal recessive type 2 (CATC2) [MIM:610019]. An opacification of the crystalline lens of the eye becoming evident at birth or in infancy. It frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. Note=Pathogenic mutations in FYCO1 can affect intracellular transport of autophagocytic vesicles from the perinuclear area to the periphery, leading to an accumulation of large numbers of vesicles and hence loss of lens transparency (PubMed:21636066).

Similarity:
Contains 1 FYVE-type zinc finger.
Contains 1 GOLD domain.
Contains 1 RUN domain.

Database links:
UniProtKB/Swiss-Prot: Q9BQS8.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 超鹏97国语| 男女插插免费视频 | 91制片厂色版在线观看 | china70years老女人 | 亚洲国产精品一二三区 | 黄色大片免费观看视频 | 911亚洲精品第一 | 日本高清一区二区视频 | 日韩天堂网 | 日韩国产中文字幕 | 国产精品99久久久久久宅男 | 亚洲AV人无码综合在线观看 | 亚洲AV无码精品色午夜果冻不卡 | 欧美精品在线一区二区三区 | 午夜视频免费 | 成人亚洲 | 91欧美视频| 啪啪网免费视频 | 美女不带套日出白浆免费视频 | 在线欧美色 | www.久久久久爱免 | 国产伦子沙发午休系列资源曝光 | 国产精品成人777 | 国产成人AV综合久久视色 | 欧洲乱码伦视频免费国产 | 亚洲av成人片在线观看 | 国产精品一品二区三区四区18 | 精品中文字幕在线2019 | 国产高清学生妹在线观看视频一区 | 国产福利资源在线 | 中文字幕AV无码不卡免费 | 国产亚洲精品久久久久久国模美 | 好黄好硬好爽免费视频一 | 亚洲国产精品视频观看 | 久久久亚洲一区二区三区 | 久久久久久国产精品美女 | 区二区欧美性插b在线视频网站 | 亚洲高清精品中出 | 欧美精品在线一区二区三区 | 521色香蕉网站在线观看 | 亚洲美腿丝袜无码专区 |