超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
9a蜜桃久久久久久免费,久久精品79国产精品,97精品视频在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FYCO1/Cy5 Conjugated antibody (bs-13237R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13237R-Cy5
英文名稱 Rabbit Anti-FYCO1/Cy5 Conjugated antibody
中文名稱 Cy5標記的鋅指蛋白FYCO1抗體
別    名 DKFZp779K1152; FLJ13335; FYCO1; FYCO1_HUMAN; FYVE and coiled coil domain containing 1; FYVE and coiled coil domain containing protein 1; FYVE and coiled-coil domain-containing protein 1; MGC126517; MGC126519; RUFY3; RUN and FYVE domain containing 3; Zinc finger FYVE domain-containing protein 7.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 167kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FYCO1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
FYCO1 is a 1,478 amino acid protein that contains one RUN domain, one GOLD domain and one FYVE-type zinc finger. Expressed in heart and skeletal muscle, FYCO1 exists as multiple alternatively spliced isoforms and may play a role in transcriptional regulation events. In response to DNA damage, FYCO1 is subject to phosphorylation, probably by ATM or ATR. The gene encoding FYCO1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Function:
May mediate microtubule plus end-directed vesicle transport.

Subunit:
Can form homodimers. Interacts (via C-terminus) with MAP1LC3B. Interacts with RAB7A; the interaction with RAB7A induces FYCO1 recruitment to late endosomal/lysosomal compartments.

Subcellular Location:
Cytoplasmic vesicle, autophagosome. Endosome. Lysosome. Note=Localizes to the external but not to the internal membrane of autophagosomes, and upon autophagosome/late endosome/lysosome fusion, it stays on the external surface of autolysosomes.

Tissue Specificity:
Expressed in heart and skeletal muscle.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

DISEASE:
Defects in FYCO1 are the cause of cataract congenital autosomal recessive type 2 (CATC2) [MIM:610019]. An opacification of the crystalline lens of the eye becoming evident at birth or in infancy. It frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. Note=Pathogenic mutations in FYCO1 can affect intracellular transport of autophagocytic vesicles from the perinuclear area to the periphery, leading to an accumulation of large numbers of vesicles and hence loss of lens transparency (PubMed:21636066).

Similarity:
Contains 1 FYVE-type zinc finger.
Contains 1 GOLD domain.
Contains 1 RUN domain.

Database links:
UniProtKB/Swiss-Prot: Q9BQS8.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 日韩中文字幕网 | 亚洲v精品 | 在线免费小视频 | 国产日本一区 | 亚洲中文字幕无码日韩精品 | 密臀av一区 | 日日夜夜添| a在线亚洲男人的天堂在线 大地资源网视频观看免费高清 | 在线观看深夜视频 | 无码国产午夜福利片在线观看 | 久久综合色鬼综合色 | 无码字幕av一区二区三区 | 国产一区二区中文 | 93久久精品日日躁夜夜躁欧美 | 国产免费成人av | 成人国产精品蜜柚视频 | 91精品国产91久久久久久青草 | 免费三级现频在线观看免费 | 亚洲真人无码永久在线 | 日韩国产精品一区二区 | 亚洲综合无码精品一区二区三区 | 91精品国产欧美一区二区 | 色.com| 中文国产日韩欧美二视频 | 日本少妇内射ⅩⅩⅩⅩXⅩ 最新精品视频2020在线视频 | 国产成人啪精品午夜网站 | 亚洲一区二区三区中文字幕在线 | 69av一区| 欧美成人精品三级一二三在线观看 | 久久青视频| 国产美女毛片 | 欧美性受xxxx黑人xxxy爽 | 97国产人人 | 久久久久久国产一级毛片清晰版 | 中国黄色生活片 | 亚洲二区三区四区 | 91麻豆精品国产片在线观看 | 国产超精品无码不卡AV | 日韩在线一区二区不卡视频 | 2020国产精品 | 国产免费一级 |