超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
久久93,九九视频69精品视频秋欲浓,亚洲熟妇丰满大屁股熟妇
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-FYCO1/PE-Cy3 Conjugated antibody (bs-13237R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13237R-PE-Cy3
英文名稱 Rabbit Anti-FYCO1/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的鋅指蛋白FYCO1抗體
別    名 DKFZp779K1152; FLJ13335; FYCO1; FYCO1_HUMAN; FYVE and coiled coil domain containing 1; FYVE and coiled coil domain containing protein 1; FYVE and coiled-coil domain-containing protein 1; MGC126517; MGC126519; RUFY3; RUN and FYVE domain containing 3; Zinc finger FYVE domain-containing protein 7.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  轉錄調節(jié)因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 167kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FYCO1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
FYCO1 is a 1,478 amino acid protein that contains one RUN domain, one GOLD domain and one FYVE-type zinc finger. Expressed in heart and skeletal muscle, FYCO1 exists as multiple alternatively spliced isoforms and may play a role in transcriptional regulation events. In response to DNA damage, FYCO1 is subject to phosphorylation, probably by ATM or ATR. The gene encoding FYCO1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Function:
May mediate microtubule plus end-directed vesicle transport.

Subunit:
Can form homodimers. Interacts (via C-terminus) with MAP1LC3B. Interacts with RAB7A; the interaction with RAB7A induces FYCO1 recruitment to late endosomal/lysosomal compartments.

Subcellular Location:
Cytoplasmic vesicle, autophagosome. Endosome. Lysosome. Note=Localizes to the external but not to the internal membrane of autophagosomes, and upon autophagosome/late endosome/lysosome fusion, it stays on the external surface of autolysosomes.

Tissue Specificity:
Expressed in heart and skeletal muscle.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

DISEASE:
Defects in FYCO1 are the cause of cataract congenital autosomal recessive type 2 (CATC2) [MIM:610019]. An opacification of the crystalline lens of the eye becoming evident at birth or in infancy. It frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. Note=Pathogenic mutations in FYCO1 can affect intracellular transport of autophagocytic vesicles from the perinuclear area to the periphery, leading to an accumulation of large numbers of vesicles and hence loss of lens transparency (PubMed:21636066).

Similarity:
Contains 1 FYVE-type zinc finger.
Contains 1 GOLD domain.
Contains 1 RUN domain.

Database links:
UniProtKB/Swiss-Prot: Q9BQS8.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 久久久久久久一区二区 | 国产亚洲精选美女久久久久 | 鲁大师在线影院免费观看 | 日本福利片在线观看 | 国产一区观看 | 日韩毛片在线看 | 国产免费又硬又黄又爽的视频喷水 | 久久夜色精品国产噜噜亚洲SV | 欧美另类一区二区三区 | 粉嫩av一区二区老牛影视 | 中文字幕日韩欧美在线 | 亚洲444KKKK在线观看无码 | 精品粉嫩国产一区二区三区 | 国产成人无码精品久久灭火器 | 欧美图片第一页 | 丰满老熟女毛片 | 久久亚洲热线2020精品 | 免费午夜影片 | 97干视频| 亚洲国产精品高潮呻吟久久 | 国产a一级片 | 操操干干 | 久久天堂综合亚洲伊人hd妓女 | 特级做a爰片毛片免费看1o8 | 国产福利资源在线 | 亚洲欧洲无码在线观看 | 欧美综合在线观看视频 | 久久riav | 国产成人精选在线观看不卡 | 成熟丰满熟妇高潮XXXXX视频 | 国产精品亚洲А∨无码播放不卡 | 特级毛片免费看 | 欧美精品999 | 四虎成人精品国产永久免费 | 99久久国产综合精品女图图等你 | 国产精品一区久久看 | 无遮挡十八禁污污网站免费 | 欧美黄页在线免费观看 | 国产伦理在线观看 | 国产视频一区三区 | 亚洲成人资源在线 |