超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
在线观看av资源,福利在线免费,国色天香免费视频日本
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-FYCO1/BF647 Conjugated antibody (bs-13237R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13237R-BF647
英文名稱 Rabbit Anti-FYCO1/BF647 Conjugated antibody
中文名稱 BF647標記的鋅指蛋白FYCO1抗體
別    名 DKFZp779K1152; FLJ13335; FYCO1; FYCO1_HUMAN; FYVE and coiled coil domain containing 1; FYVE and coiled coil domain containing protein 1; FYVE and coiled-coil domain-containing protein 1; MGC126517; MGC126519; RUFY3; RUN and FYVE domain containing 3; Zinc finger FYVE domain-containing protein 7.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 167kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FYCO1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
FYCO1 is a 1,478 amino acid protein that contains one RUN domain, one GOLD domain and one FYVE-type zinc finger. Expressed in heart and skeletal muscle, FYCO1 exists as multiple alternatively spliced isoforms and may play a role in transcriptional regulation events. In response to DNA damage, FYCO1 is subject to phosphorylation, probably by ATM or ATR. The gene encoding FYCO1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Function:
May mediate microtubule plus end-directed vesicle transport.

Subunit:
Can form homodimers. Interacts (via C-terminus) with MAP1LC3B. Interacts with RAB7A; the interaction with RAB7A induces FYCO1 recruitment to late endosomal/lysosomal compartments.

Subcellular Location:
Cytoplasmic vesicle, autophagosome. Endosome. Lysosome. Note=Localizes to the external but not to the internal membrane of autophagosomes, and upon autophagosome/late endosome/lysosome fusion, it stays on the external surface of autolysosomes.

Tissue Specificity:
Expressed in heart and skeletal muscle.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

DISEASE:
Defects in FYCO1 are the cause of cataract congenital autosomal recessive type 2 (CATC2) [MIM:610019]. An opacification of the crystalline lens of the eye becoming evident at birth or in infancy. It frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. Note=Pathogenic mutations in FYCO1 can affect intracellular transport of autophagocytic vesicles from the perinuclear area to the periphery, leading to an accumulation of large numbers of vesicles and hence loss of lens transparency (PubMed:21636066).

Similarity:
Contains 1 FYVE-type zinc finger.
Contains 1 GOLD domain.
Contains 1 RUN domain.

Database links:
UniProtKB/Swiss-Prot: Q9BQS8.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 亚洲一区二区三区精品动漫 | 日韩精品免费视频一区二区三区 | 亚洲成国产人片在线观看 | 黑人巨大两根一起挤进a片视频 | 9色porny自拍视频一区二区 | 欧美成免费A级毛片 | 波多野结衣在线观看一区二区 | 午夜春色| 免费成人黄色 | 乱子伦国产对白在线播放 | 在线观看自拍 | 国产精品久久久国产 | 青青草国产一区二区 | 免费观看国产美女裸体视频 | 97国产人妻人人爽人人澡 | 日本高清视频免费看 | 久久久精品午夜免费不卡 | 99精品免费久久久久久日本 | 日本无码潮喷A片无码高潮 欧美变态另类人妖 | 无码亚洲成A∧人片在线播放 | 国内自拍五区 | 色八区人妻在线视频 | 69免费在线视频 | 无码毛片视频一区二区三区 | 久久婷婷五月综合色国产免费观看 | 色网站综合 | 国产欧美综合一区二区三区 | 国产乱码精品一品二品 | 久热综合在线亚洲精品 | 打工女人内毛片 | 天天干夜夜透 | 国产精品无码一区二区三区免费 | VIDEOS日本熟妇人妻多毛 | 精品国产美女 | 无码人妻丰满熟妇区免费 | 亚洲看片lutube在线观看 | 久久天天躁狠狠躁夜夜不卡 | 国产精品美女久久久久av毛片 | 99国产精品久久久久久久日本竹 | 成人午夜淫片a | 丰满人妻一区二区三区无码av |