超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产午夜福利在线观看视频,欧美综合视频,无线乱码一二三区免费看
Rabbit Anti-ARHGEF18/AP Conjugated antibody (bs-7144R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7144R-AP
英文名稱 Rabbit Anti-ARHGEF18/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的G蛋白偶聯(lián)受體ARHGEF18抗體
別    名 p114RhoGEF; 114 kDa Rho specific guanine nucleotide exchange factor; ARHGEF 18; ARHGEF18; KIAA0521; MGC15913; p114 Rho GEF; p114-Rho-GEF; Rho specific guanine nucleotide exchange factor p114; Rho-specific guanine nucleotide exchange factor p114; Rho/Rac guanine nucleotide exchange factor (GEF) 18; Rho/Rac guanine nucleotide exchange factor 18; SA RhoGEF; Septin associated RhoGEF; ARHGI_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 131kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARHGEF18/p114RhoGEF
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].

Function:
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). p114RgoGEF cts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. It may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS), but does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.

Subunit:
Interacts with SEPT9; interaction may inhibit GEF activity. Interacts with Gbetagamma subunits GNB1 and GNG2.

Subcellular Location:
Cytoplasm. Note: Colocalizes with actin stress fibers.

Tissue Specificity:
Expressed in all tissues tested with highest expression in kidney and pancreas. Weakly or not expressed in liver, skeletal muscle and testis.

Similarity:
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.

Database links:

Entrez Gene: 23370 Human

Entrez Gene: 102098 Mouse

Entrez Gene: 304193 Rat

SwissProt: Q6ZSZ5 Human

SwissProt: Q6P9R4 Mouse

Unigene: 465761 Human

Unigene: 736818 Human

Unigene: 170461 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 91av视频在线看 | 免费无码一区二区三区蜜桃大 | 天天添天天操 | 尤物av无码色av无码 | 在线播放www| 在线成人免费网站 | 日本伊人精品一区二区三区介绍 | 久久精品国产99久久6动漫亮点 | 一级片无遮挡 | 欧美性生活视频网站 | 少妇一级淫片免费看 | 国产精品日本一区二区在线看麻豆 | 免费国产凹凸在线视频 | 新婚娇妻系列友人妻 | 一边做一边喷17P亚洲乱妇50P | 满春阁精品a∨在线观看 | 中文一国产一无码一日韩 | 日本伊人精品一区二区三区介绍 | 午夜精品女人裸体 | 国产精品视频一区二区三区无码 | 黄色激情网址 | 视频二区精品中文字幕 | 亚洲日韩中文字幕在线播放 | 成人久久久久久 | 一区日韩在线 | 插插天天 | 亚洲国产主播一区 | 人人99| 浓毛熟女看18p大黑p | 台湾无码AV一区二区三区 | 国产精品久久久久久成人 | 久久成年片色大黄全免费网站 | 老司机深夜福利网站 | 欧美亚洲日本国产黑白配 | 欧美激情一区二区三区四区 | 春药刺激国产老富婆露脸 | 午夜无人区免费网站 | 250pp亚洲情艺中心在线 | 黄视频网站在线看 | 久久99精品久久久久久园产越南 | 久久国产精品_国产精品 |