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Rabbit Anti-GLYCTK/BF647 Conjugated antibody (bs-13448R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13448R-BF647
英文名稱 Rabbit Anti-GLYCTK/BF647 Conjugated antibody
中文名稱 BF647標記的HBeAg結合蛋白4/甘油激酶抗體
別    名 HBEBP2; CG9886 like; GLCTK_HUMAN; Glycerate kinase; Glyctk; GLYCTK; HBeAg binding protein 2; HBeAg binding protein 4; HBeAg-binding protein 4; HBeAgBP4A; HBEBP2; HBEBP4.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  干細胞  細菌及病毒  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HBEBP2/GLYCTK
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]

Subcellular Location:
Cytoplasm and Cytoplasm. Mitochondrion.

Tissue Specificity:
Widely expressed.

DISEASE:
Defects in GLYCTK are the cause of D-glyceric aciduria (D-GA) [MIM:220120]. D-GA is a rare metabolic disease characterized by chronic metabolic acidosis and a highly variable clinical phenotype. Clinical features range from an encephalopathic presentation with seizures, microcephaly, severe mental retardation and early death, to milder manifestations with only speech delay or even normal development.

Similarity:
Belongs to the glycerate kinase type-2 family.

Database links:

Entrez Gene: 132158 Human

Entrez Gene: 235582 Mouse

Entrez Gene: 684314 Rat

Omim: 610516 Human

SwissProt: Q9BE01 Cynomolgus Monkey

SwissProt: Q8IVS8 Human

SwissProt: Q8QZY2 Mouse

SwissProt: Q0VGK3 Rat

Unigene: 415312 Human

Unigene: 335420 Mouse

Unigene: 202605 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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