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Rabbit Anti-Golgin 97/BF647 Conjugated antibody (bs-13486R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13486R-BF647
英文名稱 Rabbit Anti-Golgin 97/BF647 Conjugated antibody
中文名稱 BF647標記的高爾基體蛋白97抗體
別    名 Gap junction protein alpha 4 37kD; GOGA1_HUMAN; Golga 1; Golga1; Golgi autoantigen golgin subfamily a 1; Golgi autoantigen golgin subfamily A member 1; Golgi autoantigen golgin subfamily a1.; Golgin A1; Golgin subfamily A member 1; Golgin-97; Golgin97; MGC33154.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 88kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Golgin 9
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The GRIP family member, golgin 97, is a trans-Golgi network peripheral membrane protein with an extensive coiled-coil structure (67% alpha-helical content) and a C-terminal GRIP domain. Golgin 97 localizes exclusively on the cytoplasmic face of the Golgi and can form homodimers. Binding of golgin 97 to the Golgi membrane is mediated by the G protein family member, Arl1. Golgin 97 acts as an essential player to the cell in the form of a tethering molecule associating with tubulovesicular carriers during the trafficking from the trans-Golgi network to the recycling endosome and/or early endosome. During poxvirus infection, golgin 97 accumulates at the site of viral replication and is incorporated into virions. It associates with the insoluble fraction of the virus core protein, playing a significant role in virus replication and maturation of the virus membrane and core protein. Golgin 97 takes on a rod-like shape and, although it seemingly lacks a transmembrane domain, it protrudes from the surface of the virion envelope.

Function:
Probably involved in maintaining Golgi structure.

Subunit:
Binds RAB6A.

Subcellular Location:
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.

Similarity:
Contains 1 GRIP domain.

Database links:

Entrez Gene: 2800 Human

Entrez Gene: 76899 Mouse

Entrez Gene: 311919 Rat

Omim: 602502 Human

SwissProt: Q92805 Human

SwissProt: Q9CW79 Mouse

Unigene: 133469 Human

Unigene: 59504 Human

Unigene: 131098 Mouse

Unigene: 206017 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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