超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
热99在线,www中文在线,亚洲一区二区欧美日韩
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GPR40/BF350 Conjugated antibody (bs-13535R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13535R-BF350
英文名稱 Rabbit Anti-GPR40/BF350 Conjugated antibody
中文名稱 BF350標記的G蛋白偶聯受體40抗體
別    名 GPCR GPR40; FFA1R; FFAR 1; FFAR1; FFAR1_HUMAN; Free fatty acid receptor 1; G protein coupled receptor 40; G-protein coupled receptor 40; GPR 40; GPCR 40.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  糖尿病  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Dog, Pig, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR40
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
G protein coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G protein-coupled receptor 40 (GPR40) functions as a cell-surface receptor for long-chain free fatty acids (FFAs). FFAs provide an important energy source, but also function as signaling molecules in various pathways, notably the process of insulin secretion. In pancreatic tissue, the interaction of long chain FFAs with GPR40 amplifies glucose-stimulated insulin secretion from beta cells, suggesting a possible role for GPR40 in the treatment of diabetes associated with insulin-deficiency. Specifically, the Arg211His polymorphism in the GPR40 gene may contribute to the variation of insulin secretory capacity in Japanese men. Also, GPR40 may be involved in the control of breast cancer cell growth by fatty acids and, therefore, provide a link between fat and cancer.

Function:
Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed abundantly in pancreatic beta cells.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2864 Human

Entrez Gene: 233081 Mouse

Entrez Gene: 266607 Rat

Omim: 603820 Human

SwissProt: O14842 Human

SwissProt: Q76JU9 Mouse

SwissProt: Q8K3T4 Rat

Unigene: 248127 Human

Unigene: 425422 Mouse

Unigene: 86438 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 天天天做夜夜夜做无码 | 嫩B人妻精品一区二区三区 avav国产 | 免费又黄又硬又爽大片 | 精品色999| 国产精品女人久久久 | 人人干在线 | 在线日韩国产 | 国产精品99久久久久久宅男小说 | 日操操夜操操 | 久久精精品 | 久久国产精品免费专区 | 久久综合色鬼综合色 | 国产情趣视频在线观看 | 熟女人妇交换俱乐部 | 淫视频在线观看 | 久久国产精品嫩草影院的推荐理由 | 黄页在线观看免费 | 欧美成人精品二区三区99精品 | 国产又黄又硬又湿又黄的 | 日本乱子伦xxxx | 免费a级毛片无码a∨免费软件 | 国产成人免费av一区二区午夜 | 美女18禁裸乳裸体无遮挡的网站 | 亚洲一区二区三区AV天堂 | 男人的天堂啪啪 | 亲亲草在线视频 | 国产00粉嫩馒头一线天萌白酱 | 插插插插插插综合 | 香蕉成人国产精品免费看网站 | 黄色片日本人 | 国产成人福利在线一区 | 看亚洲黄色片 | 81精品国产乱码久久久久久 | 97视频免费在线观看 | 亚洲精品国偷拍自产在线观看蜜臀 | 亚洲中文字幕无码爆乳AV久久 | 日本地区不卡一区二区三区搜索 | 国产91丝袜香蕉在线播放 | 欧美第一在线视频 | 亚洲激精日韩激精欧美精品 | 办公室少妇激情呻吟a片在线观看 |