超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产精品久久丫,夜间福利网站,天天操人人射
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GPR40/BF488 Conjugated antibody (bs-13535R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13535R-BF488
英文名稱 Rabbit Anti-GPR40/BF488 Conjugated antibody
中文名稱 BF488標記的G蛋白偶聯受體40抗體
別    名 GPCR GPR40; FFA1R; FFAR 1; FFAR1; FFAR1_HUMAN; Free fatty acid receptor 1; G protein coupled receptor 40; G-protein coupled receptor 40; GPR 40; GPCR 40.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  糖尿病  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Dog, Pig, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR40
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
G protein coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G protein-coupled receptor 40 (GPR40) functions as a cell-surface receptor for long-chain free fatty acids (FFAs). FFAs provide an important energy source, but also function as signaling molecules in various pathways, notably the process of insulin secretion. In pancreatic tissue, the interaction of long chain FFAs with GPR40 amplifies glucose-stimulated insulin secretion from beta cells, suggesting a possible role for GPR40 in the treatment of diabetes associated with insulin-deficiency. Specifically, the Arg211His polymorphism in the GPR40 gene may contribute to the variation of insulin secretory capacity in Japanese men. Also, GPR40 may be involved in the control of breast cancer cell growth by fatty acids and, therefore, provide a link between fat and cancer.

Function:
Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed abundantly in pancreatic beta cells.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2864 Human

Entrez Gene: 233081 Mouse

Entrez Gene: 266607 Rat

Omim: 603820 Human

SwissProt: O14842 Human

SwissProt: Q76JU9 Mouse

SwissProt: Q8K3T4 Rat

Unigene: 248127 Human

Unigene: 425422 Mouse

Unigene: 86438 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 免费一区二区中文字幕 | 国产欧美综合一区二区三区 | 大地网资源在线观看免费高清 | 精品久久久久久久久久久久久久久久 | 剑来在线观看免费动漫 | 欧美成人精品第一区 | 亚洲视频无码一区 | 18禁男女污污污午夜网站免费暖暖 | 久热这里有精品 | 国产成人92精品午夜福利 | 久久国产乱子精品免费女 | 久久99操 | 一区二区的视频 | 无码视频免费一区二区 | 日韩高清不卡无码av | 天天综合亚洲色在线精品 | 精品黄色大片 | 7777精品伊久久久大香线蕉 | 日韩国产成人无码AV毛片 | 懂色中文一区二区在线播放 | 欧美熟乱妇 | 久久国产自偷自偷免费一区调 | 1000精品久久久久久久久 | 国产精品亚洲А∨无码播放不卡 | 国产欧美日韩中文久久 | 久久久久久女人 | 两性午夜色视频免费网站 | 日本一区二区三区在线不卡 | 久久精品国产网站高清综合 | 黄色片视频免费在线观看 | 大地资源网高清在线观看 | 国产精品美女www爽爽爽 | 69xx视频在线观看 | 夜爽8888视频在线观看 | 国产精品人人做人人爽人 | 麻豆精品传媒一二三区 | 亲子乱对白乱都乱了视频 | 国产精品人妻无码久久久苍井空 | 国产亚洲欧美另类久久 | 高清av熟女一区 | 少妇精品久久久一区二区三区 |