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Rabbit Anti-GPCR LGR7/BF488 Conjugated antibody (bs-15368R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-15368R-BF488
英文名稱 Rabbit Anti-GPCR LGR7/BF488 Conjugated antibody
中文名稱 BF488標記的G蛋白偶聯受體LGR7蛋白抗體
別    名 Gm1018; Leucine rich repeat containing G protein coupled receptor 7;LGR7; LGR7.1; LGR7.10; LGR7.2; MGC138347; MGC142177; Relaxin family peptide receptor 1; Relaxin receptor 1; Relaxin/insulin like family peptide receptor 1; RXFP 1; RXFP1; RXFP1; RXFP1_HUMAN; RXFPR1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Chicken, Cow, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 87kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPCR LGR7
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Function:
Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.

Similarity:
Belongs to the G-protein coupled receptor 1 family.
Contains 1 LDL-receptor class A domain.
Contains 9 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.

Database links:

Entrez Gene: 59350 Human

Entrez Gene: 381489 Mouse

Entrez Gene: 295144 Rat

Omim: 606654 Human

SwissProt: Q9HBX9 Human

SwissProt: Q6R6I7 Mouse

SwissProt: Q6R6I6 Rat

Unigene: 591686 Human

Unigene: 331086 Mouse

Unigene: 109230 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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