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Rabbit Anti-ZNF206/Gold Conjugated antibody (bs-13605R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-13605R-Gold
英文名稱 Rabbit Anti-ZNF206/Gold Conjugated antibody
中文名稱 膠體金標記的鋅指蛋白206抗體
別    名 Zfp206; Zinc finger and SCAN domain-containing protein 10; Zinc Finger Protein 206; ZSCAN10; ZSC10_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  神經生物學  干細胞  轉錄調節因子  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 80kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF206
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF206 (zinc finger protein 206), also known as ZSCAN10 (zinc finger and SCAN domain containing 10), is a 725 amino acid protein that contains one SCAN box domain and 14 C2H2-type zinc fingers. Localized to the nucleus, ZNF206 is thought to play a role in transcriptional regulation events. The gene encoding ZNF206 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Function:
Znf206 is a zinc finger protein and probable transcriptional regulator. It is expressed in embryonic stem cells and downregulated upon differentiation. Both Oct4 and Sox2 bind the znf206 gene.

Subunit:
Interacts with POU5F1/OCT4 and SOX2 (By similarity).

Subcellular Location:
Nuclear

Similarity:
Contains 14 C2H2-type zinc fingers.
Contains 1 SCAN box domain.

Database links:

Entrez Gene: 84891 Human

Entrez Gene: 332221 Mouse

SwissProt: Q96SZ4 Human

SwissProt: Q20D61 Mouse

Unigene: 334515 Human

Unigene: 270315 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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