超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国内外成人免费视频,欧美日韩乱一区二区三区,成人无码a级毛片免费
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CLCNKB/Biotin Conjugated antibody (bs-13627R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13627R-Bio
英文名稱 Rabbit Anti-CLCNKB/Biotin Conjugated antibody
中文名稱 生物素標記的氯離子通道KB抗體
別    名 Bartter syndrome type 3; Chloride channel Kb; Chloride channel kidney B; Chloride channel protein ClC-Kb; Chloride channel voltage sensitive Kb; ClC K2; ClC-K2; ClCK2; CLCKB; CLCKB_HUMAN; CLCNKB; hClC Kb; hClCKb; MGC24087; OTTHUMP00000011120; OTTHUMP00000011121; RP11 5P18.8.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  神經生物學  信號轉導  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 75kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CLCNKB
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport, and maintain cellular volume. CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla. CLC-KA plays a crucial role in urine concentration. The gene encoding human CLC-KA maps to chromosome 1p36. Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking. CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments. The gene encoding human CLC-KB maps to chromosome 1p36. Mutations in this gene cause type III Barter’s syndrome which is characterized by renal salt-wasting and low blood pressure.

Function:
Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed predominantly in the kidney.

DISEASE:
Defects in CLCNKB are the cause of Bartter syndrome type 3 (BS3) [MIM:607364]; also known as classic Bartter syndrome. It is an autosomal recessive form of often severe intravascular volume depletion due to renal salt-wasting associated with low blood pressure, hypokalemic alkalosis, hypercalciuria, and normal serum magnesium levels.
Defects in CLCNKB are a cause of Bartter syndrome type 4B (BS4B) [MIM:613090]. A digenic, recessive disorder characterized by impaired salt reabsorption in the thick ascending loop of Henle with pronounced salt wasting, hypokalemic metabolic alkalosis, and varying degrees of hypercalciuria. Bartter syndrome type 4B is associated with sensorineural deafness.

Similarity:
Belongs to the chloride channel (TC 2.A.49) family. CLCNKB subfamily.
Contains 2 CBS domains.

Database links:

Entrez Gene: 1188 Human

Entrez Gene: 56365 Mouse

Entrez Gene: 79430 Rat

Omim: 602023 Human

SwissProt: P51801 Human

SwissProt: Q9WUB6 Mouse

SwissProt: P51802 Rat

Unigene: 352243 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 超碰aⅴ人人做人人爽 | 国产成人精品在线观看 | 欧美无乱码久久久免费午夜一区 | 潘金莲一级淫片aaa 欧美综合二区 | 日韩黄色毛片 | 一二三四五社区在线高清观看 | 中文精品一区二区三区 | 啪啪免费观看网站 | 天天av天天爽 | 国产精品国产精品国产 | 免费精品自在久久 | 国产精品一区二区三区四区五区 | 亚洲一区二区三区在线网站 | 男人女人一边躁一边爽 | 久久久久久国产免费 | 久久伊人国产精品 | 97国产人妻人人爽人人澡 | 无码av片在线观看免费 | 国产黄色片免费 | 日本三级吃奶头添泬播放 | 国产农村妇女一区二区 | 18禁止观看强奷免费国产大片 | 国产成人精品日本亚洲网站 | 亚洲成人手机在线观看 | 裸体美女无遮挡免费网站 | 中文字幕乱码久久午夜 | 日韩中文字幕组 | 91caoprom最新超碰地址 | 精品视频一区二区三区 | 精品动漫无码一区二 | 给我看高清的视频在线观看片 | 亚洲成A人片在线观看中文无码 | 亚洲一区二区三区四区免费观看 | 精品久久久久久久久久国产潘金莲 | 天堂久久久久VA久久久久 | 亚洲wwwwww| 久久久这里有精品999 | 午在线亚洲男人午在线 | 香蕉成人国产精品免费看网站 | 亚洲国产一区二区三区在线观看 | a级片免费播放 |