超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
久久久久久国产精品美女,91男女,成年人网站在线免费观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-URP2/Kindlin-3/HRP Conjugated antibody (bs-13738R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13738R-HRP
英文名稱 Rabbit Anti-URP2/Kindlin-3/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標記的整合素結合性信號分子抗體
別    名 Fermitin family homolog 3; Fermitin family member 3; FERMT3; Kind3; Kindlin 3; Kindlin-3; Kindlin3; MGC10966; MIG 2; MIG2 like protein; MIG2-like protein; MIG2B; Unc 112 related protein 2; Unc-112-related protein 2; UNC112C; URP2_HUMAN; URP2SF.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, )
產品應用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 76kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human URP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Kindlin-3 is a 667 amino acid protein that localizes to both the cell membrane and the cytoplasm and contains one PH domain and one FERM domain. Expressed at high levels in lymph node tissue and at lower levels in spleen, thymus, stomach, placenta, lung, testis and small intestine, Kindlin-3 is thought to be involved in cell adhesion events and may play a role in apoptosis. Kindlin-3 is overexpressed in B-cell malignancies, suggesting that, via its ability to affect cell adhesion, Kindlin-3 may participate in tumor transformation and metastasis. Two isforms of Kindlin-3, designated short and long, exist due to alternative splicing events.

Function:
Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs).
Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.

Subcellular Location:
Cell projection; podosome. Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells.

Tissue Specificity:
Highly expressed in lymph node. Expressed in thymus, spleen and leukocytes. Weakly expressed in placenta, small intestine, stomach, testis and lung. Overexpressed in B-cell malignancies.

DISEASE:
Defects in FERMT3 are the cause of leukocyte adhesion deficiency type 3 (LAD3) [MIM:612840]; also called leukocyte adhesion deficiency 1 variant (LAD1v). LAD3 is a rare syndrome characterized by infections without pus formation in the presence of a leukocytosis combined with a Glanzmann-type bleeding disorder, resulting from a hematopoietic defect in integrin activation. Symptoms arise from an inability to activate the integrins expressed on hematopoietic cells, including platelets and leukocytes.

Similarity:
Belongs to the kindlin family.
Contains 1 FERM domain.
Contains 1 PH domain.

Database links:

Entrez Gene: 83706 Human

Entrez Gene: 525159 Cow

Entrez Gene: 108101 Mouse

Entrez Gene: 309186 Rat

Omim: 607901 Human

SwissProt: Q32LP0 Cow

SwissProt: Q86UX7 Human

SwissProt: Q8K1B8 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 熟女乱色一区二区三区 | 日韩一区免费在线观看 | 日本淫片| 穿书自救指南2樱花动漫免费观看 | 欧美一级在线观看久 | 九一视频免费在线观看 | 少妇做爰免费视频网站裸体艺术 | 亚洲成A人片在线观看中文无码 | 久久精品国产精品亚洲色婷婷 | 99国产精品久久久久99打野战 | wwwww黄色| 9区中文字幕在线 | 日韩免费视频一区二区 | 艳妇乳肉豪妇荡乳7 | 亚洲AV久久久久久久无码 | 国产第一页视频在线播放 | 欧美最猛性xxxxx亚洲精品 | 九九热精品在线 | 国产视频一区二区在线播放 | 国产精品亚洲А∨天堂网 | 久久久久久久久久久国产 | 黄色一级毛片儿 | 国产成人亚洲综合a∨婷婷图片 | 黄色视频毛片 | 日本黄色视频在线网址 | AV无码国产精品午夜A片 | 91高清在线免费观看 | 久一区二区三区 | 久久久亚洲欧洲日产AV | 久久国产大片 | 午夜视频中文字幕 | 亚欧洲精品在线视频免费观看 | 成人福利免费观看 | 国产精品成人免费一区久久羞羞 | 精品久久久久久综合日本 | 图片区小说区另类春色 | 啊好大好硬好涨h视频 | 亚洲国产精品一区二区三区四区 | 精品一区二区久久 | 五月网址 | 国产精品92 |