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Rabbit Anti-EHD1/AP Conjugated antibody (bs-14525R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-14525R-AP
英文名稱 Rabbit Anti-EHD1/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的EHD1蛋白抗體
別    名 CDABP0131; EH domain containing 1; EH domain-containing protein 1; EHD1; EHD1_HUMAN; FLJ42622; FLJ44618; H PAST; hPAST1; PAST; PAST homolog 1; PAST1; Testilin.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  生長因子和激素  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EHD1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]

Function:
Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes.

Subcellular Location:
Cell membrane. Early endosome membrane. Recycling endosome membrane. Associated with intracellular tubulovesicular structures.

Tissue Specificity:
Highly expressed in testis.

Similarity:
Contains 1 EF-hand domain.
Contains 1 EH domain.

Database links:

Entrez Gene: 10938 Human

Entrez Gene: 13660 Mouse

Entrez Gene: 293692 Rat

Omim: 605888 Human

SwissProt: Q9H4M9 Human

SwissProt: Q9WVK4 Mouse

SwissProt: Q641Z6 Rat

Unigene: 523774 Human

Unigene: 710868 Human

Unigene: 30169 Mouse

Unigene: 471458 Mouse

Unigene: 8141 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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