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Rabbit Anti-DNAH2/BF647 Conjugated antibody (bs-14363R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-14363R-BF647
英文名稱 Rabbit Anti-DNAH2/BF647 Conjugated antibody
中文名稱 BF647標記的軸絲動力蛋白2抗體
別    名 axonemal; Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2; Dnah2; DYH2_HUMAN; Dynein heavy chain 2; Dynein heavy chain domain-containing protein 3.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 507kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAH2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008]

Function:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.

Subcellular Location:
Cytoplasm; cytoskeleton; cilium axoneme.

Tissue Specificity:
Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in lung.

Similarity:
Belongs to the dynein heavy chain family.
Contains 5 TPR repeats.

Database links:

Entrez Gene: 146754 Human

SwissProt: Q9P225 Human

Unigene: 367649 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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