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Rabbit Anti-DNAH8/BF350 Conjugated antibody (bs-14367R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-14367R-BF350
英文名稱 Rabbit Anti-DNAH8/BF350 Conjugated antibody
中文名稱 BF350標記的軸絲動力蛋白8抗體
別    名 ATPase; DYH8_HUMAN; Axonemal beta dynein heavy chain 8; Ciliary dynein heavy chain 8; dynein axonemal heavy chain 8; dynein axonemal heavy polypeptide 8; dynein heavy chain 8 axonemal; hdhc9; RP1-202I21.7.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 514kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAH8
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012]

Function:
Dyneins are microtubule-associated motor protein complexes which are composed of several heavy, light, and intermediate chains. Dynein heavy chains (DHCs) are responsible for force production and ATPase activity and contain a highly conserved catalytic domain with 4 P-loop consensus motifs involved in nucleotide binding. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. Axonemal dyneins, found in flagella and cilia, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH8 is an outer arm axonemal DHC.

Subunit:
Consists of at least two heavy chains and a number of intermediate and light chains.

Subcellular Location:
Cytoplasm, cytoskeleton, cilium axoneme (By similarity).

Similarity:
Belongs to the dynein heavy chain family.

Database links:

Entrez Gene: 1769 Human

Omim: 603337 Human

SwissProt: Q96JB1 Human

Unigene: 520106 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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