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Rabbit Anti-DPCD/BF350 Conjugated antibody (bs-14413R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-14413R-BF350
英文名稱 Rabbit Anti-DPCD/BF350 Conjugated antibody
中文名稱 BF350標記的原發性纖毛運動障礙相關蛋白DPCD抗體
別    名 Deleted in a mouse model of primary ciliary dyskinesia; DKFZp566F084; dpcd; DPCD protein; DPCD_HUMAN; OTTHUMP00000020329; Protein DPCD; RP11 529I10.4; RP11-529I10.4.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  細胞生物  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DPCD
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
DPCD is a 203 amino acid protein that is expressed at higher levels during ciliated cell differentiation, suggesting that DPCD plays a role in the function or formation of ciliated cells. In primary ciliary dyskinesia (PCD), an autosomal recessive disease that is caused by mutations affecting the proper function of cilia, an exon in the DPCD gene is deleted. The phenotype of PCD is variable, though it may include symptoms such as sinus inverse totalis, infertility or otitis media. In severe cases, patients develop end-stage bronchiectasis and require a lung transplantation. DPCD is highly expressed in testis, with weak expression in heart, pancreas and skeletal muscle.

Function:
May play a role in the formation or function of ciliated cells.

Tissue Specificity:
Highly expressed in the testis. Weakly expressed in pancreas, skeletal muscle and heart. Expression increases during ciliated cell differentiation.

Similarity:
Belongs to the DPCD family.

Database links:

Entrez Gene: 25911 Human

Entrez Gene: 516908 Cow

Entrez Gene: 477800 Dog

Entrez Gene: 226162 Mouse

Entrez Gene: 294004 Rat

SwissProt: Q24K21 Cow

SwissProt: Q9BVM2 Human

SwissProt: Q8BPA8 Mouse

SwissProt: Q6AYM4 Rat

Unigene: 658128 Human

Unigene: 21978 Mouse

Unigene: 50057 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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