超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲成人中文字幕,免费不卡av网站,亚洲熟妇无码AV另类VR影视
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-cAMP-receptor protein/HRP Conjugated antibody (bs-12707R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12707R-HRP
英文名稱 Rabbit Anti-cAMP-receptor protein/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標記的腺苷受體蛋白抗體
別    名 CRP_ECOLI; cAMP-activated global transcriptional regulator CRP; Catabolite activator protein; CAP; Catabolite gene activator; cAMP receptor protein; CRP; cAMP regulatory protein.   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  轉錄調節因子  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human cAMP-receptor protein
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Escherichia coli contains more than 250 known promoters that must be activated prior to transcription. cAMP receptor protein (crp), also known as cAMP regulatory protein and catabolite gene activator, is a 210 amino acid E. coli protein that complexes with cyclic AMP and binds to specific DNA sites near the promoter, resulting in homodimeric transcription activation of more than 100 E. coli promoters. Acting as a negative regulator against its own synthesis, crp regulates transcription of several catabolite-sensitive operons. Crp activates transcription by making multiple interactions with RNA polymerase. Containing one cyclic nucleotide binding domain and one HTH crp-type DNA binding domain, crp binds DNA as a dimer to induce a severe bend in the DNA. This formation is a regulatory mechanism of crp gene expression that plays a major role in determining the molecular mechanism in gene transcription.

Function:
A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding (to consensus sequence 5'-AAATGTGATCTAGATCACATTT-3') to directly regulate the transcription of about 300 genes in about 200 operons and indirectly regulate the expression of about half the genome. There are 3 classes of CRP promoters; class I promoters have a single CRP-binding site upstream of the RNA polymerase (RNAP)-binding site, whereas in class II promoters the single CRP- and RNAP-binding site overlap, CRP making multiple contacts with RNAP. Class III promoters require multiple activator molecules, including at least one CRP dimer. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA (about 87 degrees), bringing upstream promoter elements into contact with RNAP. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP. High levels of active CRP are detrimental to growth (PubMed:16260780). Plays a major role in carbon catabolite repression (CCR). CCR involves cAMP, adenylate cyclase (cyaA), CRP and the EIIA-Glc component of the PTS (crr). In the presence of glucose EIIA-Glc is dephosphorylated, and does not activate adenylate cyclase, leading to reduced cAMP and thus decreased CRP activity. Also plays a role in many other processes (see PubMed:22573269).

Subunit:
Homodimer, which upon binding cAMP is able to bind DNA. AR1 of the upstream subunit binds to the C-terminus of RNAP subunit RpoA, AR2 of the downstream subunit binds to the N-terminus of RpoA while AR3 binds to sigma-70 (RpoD).

Database links:
UniProtKB/Swiss-Prot: P0ACJ8.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Contains 1 cyclic nucleotide-binding domain.
Contains 1 HTH crp-type DNA-binding domain.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 麻豆精品久久久久久中文字幕无码 | 中国农村熟妇性视频 | 成人欧美一区二区三区黑人 | 日韩中文字幕在线视频观看 | 中文字幕色视频 | 亚洲狠狠做深爱婷婷影院 | 成人国产免费视频 | 日韩中文字幕网 | 午夜视频在线观看一区二区 | 成人一级黄色毛片 | 真人无码国产作爱免费视频 | 日日久视频 | 在线观看免费视频资源 | 国产高潮流白浆啊免费A片动态 | 国产肥老妇视频 | 亚洲国产97色在线张津瑜 | 精品成人一区二区 | 香蕉人人精品 | xxxx中国一级片 | 国产福利资源在线 | 538国产精品一区二区免费视频 | 懂色av一区二区三区久久久 | 国产精品久久久久久久白皙女 | 亚洲日韩成人无码私人影院 | 精品国精品国产自在久国产应用 | 狠狠爱无码一区二区三区 | 天天有好逼 | 2020久久精品亚洲热综合 | 日本老妇人乱xxy | 国产精品免费久久影 | 成人18视频免费69 | 插插天天| 亚洲av无一区二区三区 | 国语自产拍在线观看对白 | 男女啪啪抽搐呻吟高潮动态图 | 欧美一级一级一级 | 国精产品99永久一区一区 | 国产美女一级做受老师 | 欧美大片18禁AAA免费视频 | 中文字幕在线观看精品视频 | 国产精品s|