超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日韩a∨,国产拍精品一二三,日本老妇xxxx
Rabbit Anti-cAMP-receptor protein/PE-Cy5 Conjugated antibody (bs-12707R-PE-Cy5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12707R-PE-Cy5
英文名稱 Rabbit Anti-cAMP-receptor protein/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標(biāo)記的腺苷受體蛋白抗體
別    名 CRP_ECOLI; cAMP-activated global transcriptional regulator CRP; Catabolite activator protein; CAP; Catabolite gene activator; cAMP receptor protein; CRP; cAMP regulatory protein.   
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞膜受體  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human cAMP-receptor protein
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Escherichia coli contains more than 250 known promoters that must be activated prior to transcription. cAMP receptor protein (crp), also known as cAMP regulatory protein and catabolite gene activator, is a 210 amino acid E. coli protein that complexes with cyclic AMP and binds to specific DNA sites near the promoter, resulting in homodimeric transcription activation of more than 100 E. coli promoters. Acting as a negative regulator against its own synthesis, crp regulates transcription of several catabolite-sensitive operons. Crp activates transcription by making multiple interactions with RNA polymerase. Containing one cyclic nucleotide binding domain and one HTH crp-type DNA binding domain, crp binds DNA as a dimer to induce a severe bend in the DNA. This formation is a regulatory mechanism of crp gene expression that plays a major role in determining the molecular mechanism in gene transcription.

Function:
A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding (to consensus sequence 5'-AAATGTGATCTAGATCACATTT-3') to directly regulate the transcription of about 300 genes in about 200 operons and indirectly regulate the expression of about half the genome. There are 3 classes of CRP promoters; class I promoters have a single CRP-binding site upstream of the RNA polymerase (RNAP)-binding site, whereas in class II promoters the single CRP- and RNAP-binding site overlap, CRP making multiple contacts with RNAP. Class III promoters require multiple activator molecules, including at least one CRP dimer. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA (about 87 degrees), bringing upstream promoter elements into contact with RNAP. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP. High levels of active CRP are detrimental to growth (PubMed:16260780). Plays a major role in carbon catabolite repression (CCR). CCR involves cAMP, adenylate cyclase (cyaA), CRP and the EIIA-Glc component of the PTS (crr). In the presence of glucose EIIA-Glc is dephosphorylated, and does not activate adenylate cyclase, leading to reduced cAMP and thus decreased CRP activity. Also plays a role in many other processes (see PubMed:22573269).

Subunit:
Homodimer, which upon binding cAMP is able to bind DNA. AR1 of the upstream subunit binds to the C-terminus of RNAP subunit RpoA, AR2 of the downstream subunit binds to the N-terminus of RpoA while AR3 binds to sigma-70 (RpoD).

Database links:
UniProtKB/Swiss-Prot: P0ACJ8.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Contains 1 cyclic nucleotide-binding domain.
Contains 1 HTH crp-type DNA-binding domain.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 亚洲欧美日韩国产高清在线观看 | 国产午夜精品视频免费不卡 | 无码毛片视频一区二区三区 | 国色天香网站 | 亚洲第一av网 | 亚洲精品久久久久久国产 | 啊好大好硬好涨h视频 | 色老综合老女人久久久 | 日韩精品在线观 | 欧美精品在线观看一区 | 美女与野兽2 | 成人影院在线观看 | 水蜜桃在线观看视频 | 午夜观看 | 日本折磨调教视频yy | 99香蕉国产精品偷在线观看 | 国产成人亚洲精品无码Av大片 | 古代性色禁片在线播放 | 在线亚洲欧美日韩精品专区 | 国产一区二区三区天码 | 国产精品亚洲精品一区二区三区 | 久久97精品久久久久久久不卡 | 国产精品视频合集 | 日韩久久久久久久久久 | 亚洲国产精品综合久久网络 | 亚洲国产日韩欧美 | 91av久久| 九九热8| 欧美日本在线播放 | 免费精品一区二区 | 色综合天天天天综合狠狠爱 | 久久男人AV资源网站 | 中日韩一级黄色片 | 91视频成人 | 精品久久久99 | 国产00粉嫩馒头一线天萌白酱 | 日日久视频 | 精品国产18久久久久久二百 | 啊好大好硬好涨h视频 | 毛片久久久久久 | 国产又黄又硬又湿又黄的 |