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Rabbit Anti-IMMP2L/Gold Conjugated antibody (bs-16620R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-16620R-Gold
英文名稱 Rabbit Anti-IMMP2L/Gold Conjugated antibody
中文名稱 膠體金標記的線粒體內膜蛋白酶樣IMP2抗體
別    名 EC 3.4.21; IMP2; IMP2 inner mitochondrial membrane peptidase like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like; IMP2 like; IMP2 like protein; IMP2-LIKE; IMP2L_HUMAN; Inner mitochondrial membrane peptidase 2 like; Mitochondrial inner membrane protease subunit 2; OTTHUMP00000207168; OTTHUMP00000207189.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  信號轉導  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IMMP2L
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011]

Function:
The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMMPL1 and IMMPL2 are the catalytic subunits of the IMP complex.

Subunit:
Heterodimer of 2 subunits, IMMPL1 and IMMPL2 (By similarity).

Subcellular Location:
Mitochondrion inner membrane; Single pass membrane protein.

Tissue Specificity:
Expressed in all tissues tested except adult liver and lung.

DISEASE:
Gilles de la Tourette syndrome (GTS) [MIM:137580]: Neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities. Note=The disease may be caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the peptidase S26 family. IMP2 subfamily.

Database links:

Entrez Gene: 83943 Human

Omim: 605977 Human

SwissProt: Q96T52 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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