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Rabbit Anti-NOSIP/PE Conjugated antibody (bs-16652R-PE)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16652R-PE
英文名稱 Rabbit Anti-NOSIP/PE Conjugated antibody
中文名稱 PE標(biāo)記的一氧化氮合成酶相互作用蛋白抗體
別    名 CGI 25; CGI-25; NOSIP_HUMAN; CGI25; CGI25 protein; eNOS interacting protein; Nitric oxide synthase interacting protein.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NOSIP
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012]

Function:
NOSIP is a novel type of modulator that promotes translocation of eNOS from the plasma membrane to intracellular sites, thereby uncoupling eNOS from plasma membrane caveolae and inhibiting NO synthesis.

Subunit:
Interacts with NOS1 and NOS3.

Subcellular Location:
Cytoplasm. Nucleus. Note: Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle.

Tissue Specificity:
Expressed in heart, brain and lung. Present in endothelial cells (at protein level).

Similarity:
Belongs to the NOSIP family.

Database links:

Entrez Gene: 51070 Human

Entrez Gene: 511234 Cow

Entrez Gene: 66394 Mouse

Entrez Gene: 292894 Rat

SwissProt: Q3SWY5 Cow

SwissProt: Q9Y314 Human

SwissProt: Q9D6T0 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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