超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲精品午夜视频,黄网亚洲,91精品视频在线免费?看
Rabbit Anti-Influenza A Nonstructural Protein 1/Gold Conjugated antibody (bs-16646R-Gold)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16646R-Gold
英文名稱 Rabbit Anti-Influenza A Nonstructural Protein 1/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的A型流感病毒非結(jié)構(gòu)蛋白1抗體
別    名 Nonstructural protein 1; NS1; NS1_I97A1; NS1A.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  細(xì)菌及病毒  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Influenza A Nonstructural Protein 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. The virus has one of sixteen possible hemagglutinin (HA) surface proteins and one of nine possible neuraminidase (NA) surface proteins. In early 2009, a novel H1N1 swine-origin influenza (S-OIV) A virus was identified in specimens obtained from patients in Mexico and the United States. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2’-5’ OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the antiviral protein kinase PKR.

Function:
Prevents the establishment of the cellular antiviral state by inhibiting TRIM25-mediated DDX58 ubiquitination, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors like IRF3 and IRF7. Prevents human EIF2AK2/PKR activation, either by binding double-strand RNA, or by interacting directly with EIF2AK2/PKR. This function may be important at the very beginning of the infection, when NS1 is mainly present in the cytoplasm. Also binds poly(A) and U6 snRNA. Suppresses the RNA silencing-based antiviral response in Drosophila cells (By similarity).

Subunit:
Homodimer. Interacts with host TRIM25 (via coiled coil); this interaction specifically inhibits TRIM25 multimerization and TRIM25-mediated DDX58 CARD ubiquitination. Interacts with human EIF2AK2/PKR, CPSF4, IVNS1ABP and PABPN1 (By similarity).

Subcellular Location:
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.

Similarity:
Belongs to the influenza A viruses NS1 family.

Database links:
SwissProt: P03496 Influenza A

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 黄片在线免费观看 | 一级黄色毛毛片 | 少妇毛片久久久久久久久 | 国产麻豆精品一区二区三区V视界 | a级片免费在线播放 | 成年人网站国产 | java性无码hd中文 | 国产精品无码A∨精品影院 女人体1963免费观看视频 | 精品国精品无码自拍自在线 | HEYZO无码综合国产精品227 | 久久久久久久午夜 | 国产真实高潮刺激太爽了 | 日韩视频在线免费观看 | 久久精品国产一区二区无码 | 日韩精品91爱爱 | 黄色一视频 | 天堂中文视频在线 | 国产欧美日韩高清在线不卡 | 成人午夜视频福利 | 欧美特级黄色 | 成人亚洲欧美一区二区三区 | 中文字幕第66页 | 丰满少妇高潮叫久久国产 | 国产人成视频在线视频 | 欧美一三区| 免费无码A片一区二区三区天美 | 欧美精品久久久久久久影视 | 特级毛片免费看 | 78影视传媒有限公司 | av网站在线观看免费 | 人妻无码中文字幕一区二区三区 | 青青草成人影院 | 九九国产精品入口麻豆 | 噜噜噜视频在线观看 | 日韩欧美综合在线视频 | 久草国产在线 | 成人午夜视频在线观看免费 | yiren22成人综合网在线 | 日本三级黄色网址 | 欧美熟妇一区二区三区蜜桃视频 | 久久av在线播放 |