超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
欧美日韩亚洲三区,91久久丝袜国产露脸动漫,日韩中文字幕a
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Influenza A Nonstructural Protein 1/PE-Cy3 Conjugated antibody (bs-16646R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-16646R-PE-Cy3
英文名稱 Rabbit Anti-Influenza A Nonstructural Protein 1/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的A型流感病毒非結構蛋白1抗體
別    名 Nonstructural protein 1; NS1; NS1_I97A1; NS1A.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細菌及病毒  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Influenza A Nonstructural Protein 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. The virus has one of sixteen possible hemagglutinin (HA) surface proteins and one of nine possible neuraminidase (NA) surface proteins. In early 2009, a novel H1N1 swine-origin influenza (S-OIV) A virus was identified in specimens obtained from patients in Mexico and the United States. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2’-5’ OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the antiviral protein kinase PKR.

Function:
Prevents the establishment of the cellular antiviral state by inhibiting TRIM25-mediated DDX58 ubiquitination, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors like IRF3 and IRF7. Prevents human EIF2AK2/PKR activation, either by binding double-strand RNA, or by interacting directly with EIF2AK2/PKR. This function may be important at the very beginning of the infection, when NS1 is mainly present in the cytoplasm. Also binds poly(A) and U6 snRNA. Suppresses the RNA silencing-based antiviral response in Drosophila cells (By similarity).

Subunit:
Homodimer. Interacts with host TRIM25 (via coiled coil); this interaction specifically inhibits TRIM25 multimerization and TRIM25-mediated DDX58 CARD ubiquitination. Interacts with human EIF2AK2/PKR, CPSF4, IVNS1ABP and PABPN1 (By similarity).

Subcellular Location:
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.

Similarity:
Belongs to the influenza A viruses NS1 family.

Database links:
SwissProt: P03496 Influenza A

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 美女黄网免费 | 伊人网综合视频 | 一级特黄大片色 | 无码人妻aⅴ一区二区三区鲁大师 | 久久99青青精品免费观看 | 少妇扒开双腿让我看个够 | 亚洲欧美乱综合图片区小说区 | 久久久久久女乱国产 | 女邻居说我的好大好硬 | 日本三级欧美三级人妇视频黑白配 | 日本高清无卡码一区二区久久 | 中文日韩欧美 | 午夜少妇在线观看视频 | 亚洲欧美日韩中文字幕在线一区 | 欧美亚洲在线 | 国产户外野战AV一级 | 国产精品高清原创巨作av | 日韩乱论 | 国产精品久久久久久不久 | 翁公粗大挺进王丽霞高潮嗨文 | 日韩午夜在线观看 | 欧美黄页在线免费观看 | 日本高清视频色 | 韩国日本中文字幕 | 国产精品色情一区二区三区 | 国产福利姬喷水福利在线观看 | 国产福利在线不卡 | www久久国产| 亚洲一区二区三区视频 | 成人影院在线免费观看 | 精品日本高清在线播放 | 欧美日韩免费做爰大片人 | 国产免费特黄淫乱片 | 99这里精品| 91免费版网址 | 日本娇小xxxⅹhd | 乱淫67194| 91人人人 | 一个色综合网 | 极品久久久久久 | 国产麻豆精品一区二区三区V视界 |