超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日本久久大片,内射老妇BBX,5555kkkk香蕉在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Influenza A Nonstructural Protein 1/PE-Cy5.5 Conjugated antibody (bs-16646R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-16646R-PE-Cy5.5
英文名稱 Rabbit Anti-Influenza A Nonstructural Protein 1/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的A型流感病毒非結構蛋白1抗體
別    名 Nonstructural protein 1; NS1; NS1_I97A1; NS1A.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細菌及病毒  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Influenza A Nonstructural Protein 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. The virus has one of sixteen possible hemagglutinin (HA) surface proteins and one of nine possible neuraminidase (NA) surface proteins. In early 2009, a novel H1N1 swine-origin influenza (S-OIV) A virus was identified in specimens obtained from patients in Mexico and the United States. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2’-5’ OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the antiviral protein kinase PKR.

Function:
Prevents the establishment of the cellular antiviral state by inhibiting TRIM25-mediated DDX58 ubiquitination, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors like IRF3 and IRF7. Prevents human EIF2AK2/PKR activation, either by binding double-strand RNA, or by interacting directly with EIF2AK2/PKR. This function may be important at the very beginning of the infection, when NS1 is mainly present in the cytoplasm. Also binds poly(A) and U6 snRNA. Suppresses the RNA silencing-based antiviral response in Drosophila cells (By similarity).

Subunit:
Homodimer. Interacts with host TRIM25 (via coiled coil); this interaction specifically inhibits TRIM25 multimerization and TRIM25-mediated DDX58 CARD ubiquitination. Interacts with human EIF2AK2/PKR, CPSF4, IVNS1ABP and PABPN1 (By similarity).

Subcellular Location:
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.

Similarity:
Belongs to the influenza A viruses NS1 family.

Database links:
SwissProt: P03496 Influenza A

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 免费中文日韩 | 国产又爽又黄又舒服又刺激视频 | 国产成人精品一区二区免费看京 | 又粗又大又黄又硬又爽免费看 | jizz大全日本护士喷奶水 | 久久久精品理论A级A片 | 加勒比AV中文字幕不卡 | 91网站在线观看视频 | 性色视频 | 国产成人啪精品视频免费软件 | 四虎永久在线精品免费一区二区 | 片多多免费观看高清 | 狠狠躁天天躁夜夜添人人 | 国产户外野战AV一级 | 日韩毛片在线看 | 黄色毛片前黄 | 激情内射亚洲一区二区三区爱妻 | 777米奇色8888狠狠俺去了 | 观看av在线 | 青青操在线观看 | 色中色登陆器 | 日本乳首の奶水在线观看视频 | 精品精品视频 | 少妇富婆一区二区三区夜夜 | 日韩av一区二区三区美女毛片 | 91夜色| 国产成人综合亚洲专区 | 亚洲国产婷婷影院 | 亚洲国产精品尤物yw在线 | 又黄又硬又湿又刺激视频免费 | 欧美一区二区视频17c | 欧美亚洲综合在线观看 | 国产操女人视频 | 一本色道精品久久一区二区三区 | 无码AV中文字幕出轨人妻 | a集毛片 | 麻豆网站免费看 | 免费视频网站 | 国产成在线观看免费视频 | 激情内射日本一区二区三区 | 国产亚洲精品久久久久久无挡照片 |