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Rabbit Anti-KCNK5/BF488 Conjugated antibody (bs-16904R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-16904R-BF488
英文名稱 Rabbit Anti-KCNK5/BF488 Conjugated antibody
中文名稱 BF488標記的鉀離子通道蛋白5抗體
別    名 Acid sensitive potassium channel protein TASK 2; Acid-sensitive potassium channel protein TASK-2; FLJ11035; K2p5.1; KCNK 5; KCNK5; KCNK5_HUMAN; Potassium channel subfamily K member 1; Potassium channel subfamily K member 5; TASK 2; TASK2; TWIK related acid sensitive K(+) channel 2; TWIK related acid sensitive K+ channel 2; TWIK-related acid-sensitive K(+) channel 2.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  神經生物學  通道蛋白  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNK5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport. [provided by RefSeq, Jul 2008]

Function:
pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.

Subcellular Location:
Membrane.

Tissue Specificity:
Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli.

Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Database links:

Entrez Gene: 8645 Human

Entrez Gene: 16529 Mouse

Omim: 603493 Human

SwissProt: O95279 Human

SwissProt: Q9JK62 Mouse

Unigene: 444448 Human

Unigene: 68998 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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