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Rabbit Anti-GSH2/APC Conjugated antibody (bs-16336R-APC)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16336R-APC
英文名稱 Rabbit Anti-GSH2/APC Conjugated antibody
中文名稱 APC標(biāo)記的GSH2蛋白抗體
別    名 GS homeobox 2; GSX2; GSX2_HUMAN; Homeobox protein GSH 2; Homeobox protein GSH-2.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)運(yùn)蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GSH2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure. The homeobox DNA-binding domain is commonly found in proteins that play a role in development and are involved in transcriptional regulation and the control of gene expression. GSH-2 (GS homeobox-2), also known as GSX2, is a 304 amino acid protein that contains one homeobox DNA-binding domain. Localized to the nucleus, GSH-2 is thought to function as a transcription factor that selectively binds the DNA sequence 5'-CNAATTAG-3'. Specifically, GSH-2 may be involved in neuronal differentiation, playing a role in spinal cord development.

Function:
Probable transcription factor that binds to the DNA sequence 5'-CNAATTAG-3' (By similarity).

Subcellular Location:
Nucleus (By similarity).

Similarity:
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 170825 Human

Entrez Gene: 14843 Mouse

Entrez Gene: 364140 Rat

SwissProt: Q9BZM3 Human

SwissProt: P31316 Mouse

Unigene: 371899 Human

Unigene: 218752 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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