超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
久操免费视频,一区一区三区四区产品动漫,羞羞答答入口
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-JDP2/Gold Conjugated antibody (bs-17200R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17200R-Gold
英文名稱 Rabbit Anti-JDP2/Gold Conjugated antibody
中文名稱 膠體金標記的JDP2蛋白抗體
別    名 Jdp2; JDP2_HUMAN; Jun dimerization protein 2; JUNDM2; Progesterone receptor co-activator.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 19kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human JDP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
c-Jun dimerization protein (JDP) 2 binds cAMP-response element (CRE) as a homodimer or as a heterodimer with ATF-2 and c-Jun. This dimerization allows JDP2 to repress CRE-dependent transcription. JDP2 is phosphorylated by c-Jun N-terminal kinase at Thr 138. JDP2 contains a basic leucine zipper (bZIP) region for DNA-binding. The bZIP region of JDP2 interacts with the DNA binding domain (DBD) of progesterone receptor (PR) in mammalian cells. Two other coactivators, creb binding protein (CBP) and p300 CBP-associated factor (PCAF), also associate with JDP2. Thus, JDP2 appears to stimulate the N-terminal activation function domain of PR by docking to the DBD and facilitation PR interaction with other coactivators. The expression of JDP2 in PR-targeted tissues and cells supports the role for JDP2 in PR function. In addition, JDP2 may play an important role in controlling the commitment of F9 embryonal carcinoma cells to differentiation. In undifferentiated F9 cells, JDP2 recruits HDAC3 and binds the differentiation response element within the c-jun promoter. Retinoic acid-induction replaces the JDP2/HDAC3 complex with PCAF and subsequently allows the transcription of c-Jun for F9 differentiation. The gene encoding human JDP2 maps to chromosome 14q24.2.

Function:
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments.

Similarity:
Belongs to the bZIP family. ATF subfamily.
Contains 1 bZIP domain.

Database links:

Entrez Gene: 122953 Human

Entrez Gene: 81703 Mouse

Entrez Gene: 116674 Rat

Omim: 608657 Human

SwissProt: Q8WYK2 Human

SwissProt: P97875 Mouse

SwissProt: Q78E65 Rat

Unigene: 196482 Human

Unigene: 103560 Mouse

Unigene: 10721 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 亚洲国产精品免费在线观看 | 国产精品啪一品二区三区粉嫩 | 欧美人妖aa1片 | 亚洲乱色 | 少妇被猛烈进入A片 | 中文字幕人妻伦伦 | chinese中国人妻4p对白视频 | 免费精品一区二区 | 性巴克一键去除衣物 | 国产全黄a一级毛片91 | 搡少妇在线视频少妇干活了 | 在线观看成人毛片 | 少妇一级淫片中文字幕 | 黄色在线观看免费 | 天天综合精品 | 国产精品成人AV在线观看 | 国产精品日产三级在线 | 一级簧片免费看 | 日本熟妇无码色视频网站VR | 欧美大片18禁AAA免费视频 | av片在线观看永久免费 | 久草在线视频新时代视频 | 性色AⅤ在线观看免费 | 国产啪爱视频精品免视 | 欧美久久一区二区三区 | 精品黑人一区二区三区久久 | 精品国精品国产自在久国产应用 | 91婷婷韩国欧美一区二区 | 亚洲中文字幕在线网址 | 免费观看国产美女裸体视频 | 日产中文字暮在线理论 | 99视频在线观看视频 | 天天干天天操天天玩 | 国产一区二区网站 | 99久久免费看精品国产一区非洲 | 国产精品国产三级国产专播 | 亚洲综合熟女久久久40P | 黑人中文字幕一区二区三区 | 久久精品一本一区人人 | 亚洲无亚洲人成网站77777 | 久久久九九 |