超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
天堂网在线WWW最新版资源,一级视频在线观看2,亚洲欧美国产日韩一区夜色
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-JDP2/AP Conjugated antibody (bs-17200R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17200R-AP
英文名稱 Rabbit Anti-JDP2/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的JDP2蛋白抗體
別    名 Jdp2; JDP2_HUMAN; Jun dimerization protein 2; JUNDM2; Progesterone receptor co-activator.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 19kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human JDP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
c-Jun dimerization protein (JDP) 2 binds cAMP-response element (CRE) as a homodimer or as a heterodimer with ATF-2 and c-Jun. This dimerization allows JDP2 to repress CRE-dependent transcription. JDP2 is phosphorylated by c-Jun N-terminal kinase at Thr 138. JDP2 contains a basic leucine zipper (bZIP) region for DNA-binding. The bZIP region of JDP2 interacts with the DNA binding domain (DBD) of progesterone receptor (PR) in mammalian cells. Two other coactivators, creb binding protein (CBP) and p300 CBP-associated factor (PCAF), also associate with JDP2. Thus, JDP2 appears to stimulate the N-terminal activation function domain of PR by docking to the DBD and facilitation PR interaction with other coactivators. The expression of JDP2 in PR-targeted tissues and cells supports the role for JDP2 in PR function. In addition, JDP2 may play an important role in controlling the commitment of F9 embryonal carcinoma cells to differentiation. In undifferentiated F9 cells, JDP2 recruits HDAC3 and binds the differentiation response element within the c-jun promoter. Retinoic acid-induction replaces the JDP2/HDAC3 complex with PCAF and subsequently allows the transcription of c-Jun for F9 differentiation. The gene encoding human JDP2 maps to chromosome 14q24.2.

Function:
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments.

Similarity:
Belongs to the bZIP family. ATF subfamily.
Contains 1 bZIP domain.

Database links:

Entrez Gene: 122953 Human

Entrez Gene: 81703 Mouse

Entrez Gene: 116674 Rat

Omim: 608657 Human

SwissProt: Q8WYK2 Human

SwissProt: P97875 Mouse

SwissProt: Q78E65 Rat

Unigene: 196482 Human

Unigene: 103560 Mouse

Unigene: 10721 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 日本人妻丰满熟妇久久久久久 | 色综合久久网 | 国产人成在线视频免费播放 | 人妻中文av无码。久久 | 黄色片一级毛片 | 91精品国产一区二区三区在线 | 国产精品久久久久久久hd | 亚洲午夜国产成人 | 91天堂国产在线 | 欧美大片aaaa | 成人高清videosex高潮 | 欧美一及| 人人妻人人玩人人澡人人爽 | 91中文啦 | 亚日韩一区 | 豪放女大兵在线 | 亚洲AV无码专区亚洲AV紧身裤 | 成人国产免费软件 | 男男无码sm调教gv资源 | 国产真实露脸乱子伦 | 午夜资源在线 | 国产精品免费看久久久软件 | 成人免费777777被爆出 | 亚洲欧美国产日韩综合 | 嗯快点别停舒服好爽受不了了 | 日韩一区二区免费在线观看 | 成人在线国产 | 99小视频在线观看 | 精品一区在线 | 穿书自救指南2樱花动漫免费观看 | 天体野营在线 | 亚洲av日韩av成人av | 少妇愉情理伦片丰满丰满 | 99精品久久久国产一区二区三 | 美国经典三级 | 亚洲一级久久 | 美日韩一区二区三区 | 男人操女人免费网站 | 免费的性视频越黄越好 | 国产精品毛片a∨一区二区三区 | 日韩片一区|