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Rabbit Anti-KIAA1688/PE-Cy3 Conjugated antibody (bs-17022R-PE-Cy3)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-17022R-PE-Cy3
英文名稱(chēng) Rabbit Anti-KIAA1688/PE-Cy3 Conjugated antibody
中文名稱(chēng) PE-Cy3標(biāo)記的KIAA1688蛋白抗體
別    名 ARHGAP39; CrGAP; RHG39_HUMAN; Uncharacterized protein KIAA1688; Vilse.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 121kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIAA1688
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. KIAA1688, also known as ARHGAP39 (Rho GTPase activating protein 39), CrGAP or Vilse, is a 1,083 amino acid nuclear protein that contains one MyTH4 domain, one Rho-GAP domain and two WW domains. KIAA1688 is encoded by a gene located on human chromosome 8, which consists of nearly 146 million bases and encodes approximately 800 genes. Chromosome 8 is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.

Function:
KIAA1688 was identified as a hypothetical protein predicted from the in silico analysis of long cDNAS isolated in the Kazusa cDNA sequencing project. The function of KIAA1688 has not been characterized.

Subcellular Location:
Nuclear

Similarity:
Contains 1 MyTH4 domain.
Contains 1 Rho-GAP domain.
Contains 2 WW domains.

Database links:

Entrez Gene: 80728 Human

SwissProt: Q9C0H5 Human

SwissProt: P59281 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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