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Rabbit Anti-Kir2.2/APC Conjugated antibody (bs-17068R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17068R-APC
英文名稱 Rabbit Anti-Kir2.2/APC Conjugated antibody
中文名稱 APC標記的鉀離子通道Kir2.2抗體
別    名 ATP sensitive inward rectifier potassium channel 12; ATP-sensitive inward rectifier potassium channel 12; hIRK; Human high conductance inward rectifier potassium channel alpha; Inward rectifier K; Inward rectifier K(+) channel Kir2.2; Inward rectifier K(+) channel Kir2.2v; inwardly rectifying subfamily J member 12; IRK-2; IRK12_HUMAN; IRK2; KCNJ12; kcnj12x; KCNJN1; Kir2.2v; Potassium channel; Potassium channel inwardly rectifying subfamily J member 12; Potassium inwardly rectifying channel subfamily J member 12; Potassium inwardly rectifying channel,subfamily J inhibitor 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Kir2.2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.

Subcellular Location:
Membrane.

Similarity:
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
KCNJ12 subfamily.

Database links:

Entrez Gene: 403760 Dog

Entrez Gene: 100131509 Human

Entrez Gene: 100290070 Human

Entrez Gene: 3768 Human

Entrez Gene: 16515 Mouse

Entrez Gene: 117052 Rat

Omim: 602323 Human

SwissProt: Q4TZY1 Cow

SwissProt: Q14500 Human

SwissProt: P52187 Mouse

SwissProt: P52188 Rat

Unigene: 200629 Human

Unigene: 4970 Mouse

Unigene: 10406 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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