超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
人人妻人人爽人人澡AV,色爽爽爽,九一传媒在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-TNNI3/BF647 Conjugated antibody (bs-10614R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-10614R-BF647
英文名稱 Rabbit Anti-TNNI3/BF647 Conjugated antibody
中文名稱 BF647標記的心肌肌鈣蛋白I抗體
別    名 Cardiac Troponin I; cardiac muscle; Troponin I, cardiac muscle; Cardiomyopathy, familial hypertrophic, 7, included; CMD1FF; CMD2A; CMH7; cTnI; Familial hypertrophic cardiomyopathy 7; MGC116817; RCM1; Tn1; Tni; TNN I3; TNNC 1; TNNC1; TNNI3; TNNI3; TNNI3_HUMAN; Troponin I; Troponin I cardiac; Troponin I cardiac muscle; Troponin I cardiac muscle isoform; Troponin I type 3 cardiac; troponin I, cardiac 3; TroponinI; Ttroponin I type 3 (cardiac).  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  發育生物學  信號轉導  干細胞  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNNI3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq].

Function:
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Post-translational modifications:
Phosphorylated at Ser-42 and Ser-44 by PRKCE; phosphorylation increases myocardium contractile dysfunction. Phosphorylated at Ser-23 and Ser-24 by PRKD1; phosphorylation reduces myofilament calcium sensitivity. Phosphorylated preferentially at Thr-31. Phosphorylation by STK4/MST1 alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T).

DISEASE:
Defects in TNNI3 are the cause of cardiomyopathy familial hypertrophic type 7 (CMH7) [MIM:613690]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
Defects in TNNI3 are the cause of cardiomyopathy familial restrictive type 1 (RCM1) [MIM:115210]. RCM1 is an heart muscle disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.
Defects in TNNI3 are the cause of cardiomyopathy dilated type 2A (CMD2A) [MIM:611880]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
Defects in TNNI3 are the cause of cardiomyopathy dilated type 1FF (CMD1FF) [MIM:613286]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Similarity:
Belongs to the troponin I family.

Database links:

Entrez Gene: 493744 Cat

Entrez Gene: 511094 Cow

Entrez Gene: 403566 Dog

Entrez Gene: 7137 Human

Entrez Gene: 21954 Mouse

Entrez Gene: 100049696 Pig

Entrez Gene: 29248 Rat

Omim: 191044 Human

SwissProt: Q863B6 Cat

SwissProt: P08057 Cow

SwissProt: Q8MKD5 Dog

SwissProt: P19429 Human

SwissProt: P48787 Mouse

SwissProt: P02646 Rabbit

SwissProt: P23693 Rat

Unigene: 709179 Human

Unigene: 27674 Mouse

Unigene: 64141 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 天天爱天天射天天干 | 丝袜a∨在线一区二区三区不卡 | 欧美日韩欧美日韩在线观看视频 | 国产毛片a | 亚洲日本欧美天堂在线手机版 | 国产一国产一级毛片视频 | 久草在线免费资源 | 国产精品黑人富婆视频区 | 国产免费特黄淫乱片 | 中国一级伦理片 | 日本三级无码中文字幕 | 亚洲一区精品在线观看 | WWW亚洲色大成网络.COM | www.色噜噜| 日本97av | 一级片久久久久久 | 93人妻人人揉人人澡人人 | 夜夜久久久 | 精品一区二区久久 | 久久精品国产99国产精品亚洲 | 欧美三级不卡在线播放 | 人和牛交VIDE欧美 | 日韩中文字幕网 | 亚洲精品国偷拍自产在线观看蜜臀 | chinese中国人妻4p对白视频 | 中文字幕_第3页_高清免费在线 | 91亚洲国产成人精品性色 | 延禧攻略免费在线观看 | 久久人人爽人人爽人人片av高请 | 久久欧美视频 | 国产热A欧美热A在线视频 | 不卡高清视频 | 日韩人妻无码精品系列专区 | Chinese国产高清Av | 四虎影视在线视频大全免费观看 | 妺妺窝人体色WWW网 粉嫩小仙女扒开双腿自慰 明星ai换脸二三区入口 | mmm·www看片免费观看 | 亚洲AV人无码综合在线观看 | 永久555www成人免费 | 永久av在线 | 久久久久久久久久久久久久久伊免 |