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Rabbit Anti-MON2/AP Conjugated antibody (bs-17713R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17713R-AP
英文名稱 Rabbit Anti-MON2/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的MON2蛋白抗體
別    名 mon2; MON2_HUMAN; Protein MON2 homolog; Protein SF21; SF21.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
產品應用 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 190kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MON2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
MON2 is a 1,718 amino acid protein that exists as multiple alternatively spliced isoforms and plays an important role in membrane trafficking. Related to the guanine nucleotide exchange factors (GEFs), MON2 shares significant homology with BIG as well as the GBF (Golgi brefeldin A resistance factor) subfamilies of proteins. MON2 acts as a scaffold protein when associated with Dopey-1, a large cytoplasmic protein involved in trafficking between the late golgi and early endosomes. MON2 is homologous to the yeast protein and is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Function:
May be required for traffic between late Golgi and early endosomes.

Similarity:
Belongs to the MON2 family.

Database links:

Entrez Gene: 23041 Human

Entrez Gene: 314894 Rat

SwissProt: Q7Z3U7 Human

Unigene: 389378 Human

Unigene: 154642 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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