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Rabbit Anti-LMO1/PE-Cy5.5 Conjugated antibody (bs-18313R-PE-Cy5.5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-18313R-PE-Cy5.5
英文名稱 Rabbit Anti-LMO1/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的T淋巴細胞轉(zhuǎn)運蛋白1抗體
別    名 Cysteine rich protein TTG 1; Cysteine rich protein TTG1; LIM domain only 1; LIM domain only protein 1; LMO 1; MGC116692; RBTN 1; RBTN1; RHOM 1; RHOM1; Rhombotin 1; Rhombotin1; T cell translocation protein 1; TTG 1; TTG1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  轉(zhuǎn)運蛋白  淋巴細胞  t-淋巴細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Chicken, Pig, Cow, Rabbit, Zebrafish, Guinea Pig, Monkey, Cat,  Spider Monkey)
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LMO1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2012]

Function:
May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.

Subcellular Location:
Nuclear

Tissue Specificity:
Expressed mainly in the central nervous. Low level of expression in other tissues including thymus.

DISEASE:
A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p15;q11) with TCRD.

Similarity:
Contains 2 LIM zinc-binding domains.

Database links:

Entrez Gene: 27152 Cow

Entrez Gene: 4004 Human

Entrez Gene: 109594 Mouse

Entrez Gene: 245979 Rat

Entrez Gene: 280646 Zebrafish

Omim: 186921 Human

SwissProt: Q0P5B3 Cow

SwissProt: P25800 Human

SwissProt: Q924W9 Mouse

SwissProt: Q8JFQ2 Zebrafish

Unigene: 654426 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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