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Rabbit Anti-LRP3/BF488 Conjugated antibody (bs-18364R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18364R-BF488
英文名稱 Rabbit Anti-LRP3/BF488 Conjugated antibody
中文名稱 BF488標記的低密度脂蛋白受體相關蛋白3抗體
別    名 105 kDa low-density lipoprotein receptor-related protein; hLRp105; Low density lipoprotein receptor related protein 3; Low-density lipoprotein receptor-related protein 3; LRP-3; Lrp3; LRP3_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  細胞膜受體  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 79kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LRP3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Low-density lipoprotein receptor-related protein 3 (LRP3) is a 770 amino acid protein that contains two CUB domains and four LDL-receptor class A domains. LRP3 is widely expressed with highest expression in skeletal muscle and ovary and lowest expression in testis, colon and leukocytes. LRP3 is potentially a membrane receptor involved in the internalization of lipophilic molecules and/or signal transduction.

Function:
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.

Subcellular Location:
Membrane. Membrane > coated pit.Target information above from: UniProt accession O75074 The UniProt Consortium The Universal Protein Resource (UniProt) in 2010 Nucleic Acids Res. 38:D142-D148 (2010) .

Tissue Specificity:
Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.

Similarity:
Belongs to the LDLR family.
Contains 2 CUB domains.
Contains 4 LDL-receptor class A domains.

Database links:

Entrez Gene: 4037 Human

Entrez Gene: 435965 Mouse

Entrez Gene: 89787 Rat

Omim: 603159 Human

SwissProt: O75074 Human

SwissProt: O88204 Rat

Unigene: 515340 Human

Unigene: 273631 Mouse

Unigene: 145216 Rat

Unigene: 87059 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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