超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲一区二区四区蜜桃,欧美日韩第一页,黄的网站在线观看
Rabbit Anti-PIP5K3/Cy3 Conjugated antibody (bs-18540R-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-18540R-Cy3
英文名稱 Rabbit Anti-PIP5K3/Cy3 Conjugated antibody
中文名稱 Cy3標(biāo)記的磷脂酰肌醇3磷酸激酶5Ⅲ型抗體
別    名 1-phosphatidylinositol-3-phosphate 5-kinase; 1 phosphatidylinositol 3 phosphate 5 kinase; 1 phosphatidylinositol 4 phosphate 5 kinase; CFD; FAB1; FYVE finger containing phosphoinositide kinase; KIAA0981; MGC40423; p235; Phosphatidylinositol 3 phosphate 5 kinase type III; Phosphatidylinositol 3 phosphate/phosphatidylinositol 5 kinase type III; Phosphatidylinositol 4 phosphate 5 kinase type III; Phosphoinositide kinase, FYVE finger containing; PIKFYVE; PIP5K; PIPkin III; PtdIns(4)P 5 kinase; Type III PIP kinase; ZFYVE29; Zinc finger, FYVE domain containing 29.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 237kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PIP5K3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns. In contrast, PIKfyve preferentially phosphorylates D-3 phosphorylated PtdIns. In addition to being a lipid kinase, PIKfyve also has protein kinase activity. PIKfyve regulates endomembrane homeostasis and plays a role in the biogenesis of endosome carrier vesicles from early endosomes. Mutations in this gene cause corneal fleck dystrophy (CFD); an autosomal dominant disorder characterized by numerous small white flecks present in all layers of the corneal stroma. Histologically, these flecks appear to be keratocytes distended with lipid and mucopolysaccharide filled intracytoplasmic vacuoles. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]

Function:
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.

Subcellular Location:
Endosome membrane

Post-translational modifications:
Phosphorylated in response to insulin at Ser-318 in a protein kinase B (PKB)-dependent manner.

DISEASE:
Corneal dystrophy, fleck (CFD) [MIM:121850]: A form of stromal corneal dystrophy characterized by numerous small white flecks scattered in all levels of the stroma, with configurations varying from semicircular to wreath-like, curvilinear, or punctate. Although CFD may occasionally cause mild photophobia, patients are typically asymptomatic and have normal vision.

Similarity:
Contains 1 DEP domain.
Contains 1 FYVE-type zinc finger.
Contains 1 PIPK domain.

Database links:

Entrez Gene: 200576 Human

Omim: 609414 Human

SwissProt: Q9Y2I7 Human

Unigene: 173939 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 亚洲国产精品一区二区三区四区 | 天天综合网久久 | 日韩成人av片 | 亚洲午夜无码AV毛片久久 | 日韩视频在线一区二区 | 久久久久久1| 好硬好湿好爽再深一点动态图视频 | 麻豆视频免费在线 | 国产精品毛片av一区 | 国产一级黄色小视频 | 久久免费公开视频 | 99久久免费国产精品四虎 | 亚洲一卡二卡三卡四卡无卡网站 | 久久免费看少妇高潮a片特黄 | 欧美日韩国产一区二区三区在线 | 少妇人妻偷人精品视蜜桃 | 亚洲AV无码精品色午夜果冻不卡 | 亚洲AV无码片区一区二区三区 | 国产在线午夜 | 欧美大片18禁AAA免费视频 | 国产精品欧美久久久 | 777黄色 | 男人和女人啪啪网站 | 在线观看人成 | 午夜天堂成人欧美www无码 | 成年女人看片永久免费视频 | 亚洲av无码久久精品成人 | 91av资源九色蝌蚪视频 | 久久亚洲AV无码精品色午夜 | 久热精品视频在线免费观看 | 夜夜草天天草 | 亚洲AV成人无码精品网站老司机 | 健身房啪啪的av片 | 最近2018免费中文字幕4 | 亚洲国产精品美女久久久久 | 香港经典av三级观看 | 夜夜骑日日 | 毛片无遮挡高清免费 | 鲁大师在线影院免费观看 | 国产成人av免费 | 精品一区影院 |