超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
成人午夜做爰视频免费看,快色视频,国产精品不卡一区
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-MAK (Tyr159)/BF488 Conjugated antibody (bs-18634R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18634R-BF488
英文名稱 Rabbit Anti-phospho-MAK (Tyr159)/BF488 Conjugated antibody
中文名稱 BF488標記的磷酸化絲氨酸/蘇氨酸蛋白激酶MAK抗體
別    名 MAK (phospho Tyr159); MAK (phospho Y159); dJ417M14.2; Mak; MAK_HUMAN; Male germ cell associated kinase; Male germ cell-associated kinase; OTTHUMP00000016025; Rck; Serine/threonine protein kinase MAK; Serine/threonine-protein kinase MAK.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 細胞生物  發育生物學  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human MAK around the phosphorylation site of Tyr159
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Function:
Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis.
May play a role in chromosomal stability in prostate cancer cells.

Subcellular Location:
Nucleus. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Midbody. Cell projection > cilium > photoreceptor outer segment. Photoreceptor inner segment. Localized in both the connecting cilia and the outer segment axonemes (By similarity). Localized uniformly in nuclei during interphase, to the mitotic spindle and centrosomes during metaphase and anaphase, and also to midbody at anaphase until telophase.

Tissue Specificity:
Expressed in prostate cancer cell lines at generally higher levels than in normal prostate epithelial cell lines. Isoform 1 is expressed in kidney, testis, lung, trachea, and retina. Isoform 2 is retina-specific where it is expressed in rod and cone photoreceptors.

Post-translational modifications:
Autophosphorylated. Phosphorylated on serine and threonine residues.

DISEASE:
Defects in MAK are the cause of retinitis pigmentosa type 62 (RP62) [MIM:614181]. RP62 is a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

Similarity:
Belongs to the protein kinase superfamily.
CMGC Ser/Thr protein kinase family.
CDC2/CDKX subfamily. Contains 1 protein kinase domain.

Database links:

Entrez Gene: 4117 Human

Entrez Gene: 17152 Mouse

Entrez Gene: 25677 Rat

Omim: 154235 Human

SwissProt: P20794 Human

SwissProt: Q04859 Mouse

SwissProt: P20793 Rat

Unigene: 446125 Human

Unigene: 8149 Mouse

Unigene: 9670 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 老司机avhd101高清 | 天天骑天天干 | 久久久久久国产一级毛片清晰版 | 国产成人精品亚洲日本在线桃色 | 国产精品久久久aaa 欧美乱强伦XXXXX | 亚洲成人日韩 | 1000部啪啪未满十八勿入 | 国产免费无遮挡吸乳视频 | 无码AV中文字幕出轨人妻 | 国产精品亚洲三区 | 久久爽久久爽久久免费观看 | 无码av片在线观看免费 | 一级片久久免费 | 久久99精品国产.久久久久 | 欧美黑人巨大XXXXX视频 | 男女啪啪免费观看无遮挡 | 亚洲综合无码精品一区二区三区 | 理论片午午伦夜理片I | chinese老太性视频bbw | 日韩精品一区二区三区丰满 | 国产精品一级毛片无码老人 | 2020久久精品亚洲热综合 | 国产精品女A片爽爽波多野结衣 | 国产精品美女久久久久久久久久久 | 精品视频只有精品高清6 | 在线观看91av | 国产高清精品一区二区三区 | 老师好湿好紧我要进去了在线观看 | 国产一国产二国产三国产四国产五 | 18禁无遮挡啪啪无码网站 | 国产中文字幕乱人伦在线观看 | 中文字幕亚洲综合 | 粉嫩av一区二区老牛影视 | 94一欧美一setu | 一级片在线免费播放 | 中国av免费在线观看 | 激情中文网 | 久久国产精选 | 男女人xx视频 | 日韩av免费无码一区二区三区 | 国产高清免费av |