超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产精品香蕉在线观看,在线看片免费人成视频大全,日本视频a
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-MBNL2/Gold Conjugated antibody (bs-18707R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-18707R-Gold
英文名稱 Rabbit Anti-MBNL2/Gold Conjugated antibody
中文名稱 膠體金標記的盲肌樣RNA結合蛋白MBNL2抗體
別    名 DKFZp781H1296; MBLL; MBLL39; Mbnl2; MBNL2_HUMAN; MGC120625; MGC120626; MGC120628; Muscleblind like 2; muscleblind like protein 1; muscleblind like protein 2; muscleblind like protein like 39; muscleblind like splicing regulator 2; Muscleblind-like protein 1; Muscleblind-like protein 2; Muscleblind-like protein-like 39; Muscleblind-like protein-like; OTTHUMP00000178763; PRO2032; RP11-128N14.1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MBNL2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. [provided by RefSeq, Mar 2012]

Function:
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. RNA-binding protein that binds to 5'ACACCC-3' core sequence, termed zipcode, within the 3'UTR of ITGA3. Binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. Seems to regulates expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm at adhesion plaques. May play a role in myotonic dystrophy pathophysiology (DM).

Subcellular Location:
Nucleus. Cytoplasm. Greater concentration in the nucleus. Expressed in or near large cytoplasmic adhesion plaques. Location in the cytoplasm is microtubule-dependent. In both DM1 and DM2 patients, colocalizes with nuclear foci of retained expanded-repeat transcripts.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the muscleblind family.
Contains 4 C3H1-type zinc fingers.

Database links:

Entrez Gene: 10150 Human

Entrez Gene: 105559 Mouse

Entrez Gene: 680445 Rat

Omim: 607327 Human

SwissProt: Q5VZF2 Human

SwissProt: Q8C181 Mouse

SwissProt: F2Z3T4 Rat

Unigene: 657347 Human

Unigene: 238266 Mouse

Unigene: 1940 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 性欧美亚洲xxxx乳在线观看 | FREEZEFRAME丰满老妇 | JAPANESE日本熟妇喷水 | 欧美一级一级一级 | 久久国产人妻无码一区 | 亚洲AV综合永久无码精品天堂 | 九九久久婷婷 | 91制片厂色版在线观看 | 久久东京 | 国产激情久久久久老熟女亚洲 | 精品一区二区三卡四卡网站 | 成年男人裸j网站 | av中文无码乱人伦 | 久久毛片免费观看 | 国产gv在线观看受被做哭 | 色播久久人人爽人人爽人人片av | 欧美性色黄大片 | 日韩人妻无码中文字幕视频 | 97无码免费人妻超级碰碰碰碰 | 精品久久久久久久久久久久久久久久久久久 | 日韩在线视频观看免费网站 | 中文字幕一区二区三区久久 | 欧美亚洲激情 | 精品国产福利久久久 | 久久久久久久久免费视频 | 国色天香卡一卡二乱码 | 欧美一级淫片aaaaaaa视频 | 日本很黄的打屁股网站 | 亚洲成人一 | 麻豆传媒免费看 | 国产精品91av| 久久福利网站 | 羞羞视频日本动漫免费网站 | 日韩一区中文字幕 | 国产亚洲人成网站在线观看 | 美女搞久久 | 99久久人妻无码精品系列蜜桃 | 男女做爰猛烈动高潮a片免费应用 | 777亚洲熟妇自拍无码区 | 美国十次狠狠色综合AV | 97日本xxxxxxxxx18|