超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
av在线日,4455成人免费观看,男人插女人的免费视频
Rabbit Anti-MBNL2/BF350 Conjugated antibody (bs-18707R-BF350)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-18707R-BF350
英文名稱 Rabbit Anti-MBNL2/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的盲肌樣RNA結(jié)合蛋白MBNL2抗體
別    名 DKFZp781H1296; MBLL; MBLL39; Mbnl2; MBNL2_HUMAN; MGC120625; MGC120626; MGC120628; Muscleblind like 2; muscleblind like protein 1; muscleblind like protein 2; muscleblind like protein like 39; muscleblind like splicing regulator 2; Muscleblind-like protein 1; Muscleblind-like protein 2; Muscleblind-like protein-like 39; Muscleblind-like protein-like; OTTHUMP00000178763; PRO2032; RP11-128N14.1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 結(jié)合蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MBNL2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. [provided by RefSeq, Mar 2012]

Function:
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. RNA-binding protein that binds to 5'ACACCC-3' core sequence, termed zipcode, within the 3'UTR of ITGA3. Binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. Seems to regulates expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm at adhesion plaques. May play a role in myotonic dystrophy pathophysiology (DM).

Subcellular Location:
Nucleus. Cytoplasm. Greater concentration in the nucleus. Expressed in or near large cytoplasmic adhesion plaques. Location in the cytoplasm is microtubule-dependent. In both DM1 and DM2 patients, colocalizes with nuclear foci of retained expanded-repeat transcripts.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the muscleblind family.
Contains 4 C3H1-type zinc fingers.

Database links:

Entrez Gene: 10150 Human

Entrez Gene: 105559 Mouse

Entrez Gene: 680445 Rat

Omim: 607327 Human

SwissProt: Q5VZF2 Human

SwissProt: Q8C181 Mouse

SwissProt: F2Z3T4 Rat

Unigene: 657347 Human

Unigene: 238266 Mouse

Unigene: 1940 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: cao榴| 91精产国品一二三区在线观看 | 精品国产亚洲一区 | 2018天天操| av大片在线免费观看 | 麻豆影视免费观看 | 不卡一不卡二不卡三 | 欧美69精品久久久久久不卡 | 午夜精品久久 | www.俺去了| 亚洲成av人片在线观看麦芽 | 午夜欧美一区二区三区免费观看 | 国产精品一区二区a | 一级免费特黄视频 | 无码人妻一区二区三区免费看成人 | 欧美疯狂xxxxbbbb动态图 | 岛国在线视频网站 | 国产丨综合丨精品入口 | 日本无码一区二区三区在线观看 | 青青草原综合久久大伊人 | 涩五月婷婷 | 韩日精品一区 | 亚洲精品久久久久久国产 | 亚洲iv一区二区三区 | 午夜男女羞羞爽爽爽视频 | 亚州中文字幕在线观看 | 免费在线观看成人 | 久久精品国产视频 | 欧美特级黄色 | 国产特级全黄一级毛片 | 九九99靖品免费 | 亚洲一级色片 | 野花韩国高清免费视频6 | 国产JJZZJJZZ视频全部免费 | 在线视频国产一区 | 国产人人爱| 日本高清VA在线播放 | www.爱爱视频 | 国内精品久久久久久久影视麻生 | 麻豆私人影院 | 日本BBW丰满牲交片 a级片免费播放 |