超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产一线产区二线产区,国产精品一区二区3区,国内久久免费视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-MBNL2/BF647 Conjugated antibody (bs-18707R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18707R-BF647
英文名稱 Rabbit Anti-MBNL2/BF647 Conjugated antibody
中文名稱 BF647標記的盲肌樣RNA結合蛋白MBNL2抗體
別    名 DKFZp781H1296; MBLL; MBLL39; Mbnl2; MBNL2_HUMAN; MGC120625; MGC120626; MGC120628; Muscleblind like 2; muscleblind like protein 1; muscleblind like protein 2; muscleblind like protein like 39; muscleblind like splicing regulator 2; Muscleblind-like protein 1; Muscleblind-like protein 2; Muscleblind-like protein-like 39; Muscleblind-like protein-like; OTTHUMP00000178763; PRO2032; RP11-128N14.1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MBNL2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. [provided by RefSeq, Mar 2012]

Function:
Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. RNA-binding protein that binds to 5'ACACCC-3' core sequence, termed zipcode, within the 3'UTR of ITGA3. Binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. Seems to regulates expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm at adhesion plaques. May play a role in myotonic dystrophy pathophysiology (DM).

Subcellular Location:
Nucleus. Cytoplasm. Greater concentration in the nucleus. Expressed in or near large cytoplasmic adhesion plaques. Location in the cytoplasm is microtubule-dependent. In both DM1 and DM2 patients, colocalizes with nuclear foci of retained expanded-repeat transcripts.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the muscleblind family.
Contains 4 C3H1-type zinc fingers.

Database links:

Entrez Gene: 10150 Human

Entrez Gene: 105559 Mouse

Entrez Gene: 680445 Rat

Omim: 607327 Human

SwissProt: Q5VZF2 Human

SwissProt: Q8C181 Mouse

SwissProt: F2Z3T4 Rat

Unigene: 657347 Human

Unigene: 238266 Mouse

Unigene: 1940 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 91不卡 | 久热国产精品视频 | 97人人添人澡人人爽超碰动图 | 精品无码人妻一区二区三区不卡 | 东京热无码AV在线 | 国产骚妻 | 国产农村妇女一区二区 | 还珠格格第二部1至48集免费观看 | 久久黄色录像 | 久热RE这里精品视频在线6 | 1000部啪啪未满十八勿入 | 正在播放白领少妇第一次 | 学生妹av| 国产亚洲精久久久久久无码77777 | 精品国产一区三区 | 国产亚洲精品美女 | 人妻少妇被粗大爽.9797pw | 黄色在线免费视频 | 国产成人亚洲综合a∨婷婷图片 | 黄色视频毛片 | 国产成人无码精品久久久小说 | 国产精品久久久久久影视不卡 | 国产无套无码AⅤ在线观看 91精品国产一区二区三区在线 | 99精品在线视频播放 | 图片区小说区另类春色 | 国产一级片免费视频 | 亚洲AV成人无码一区无广告 | 中国人妻与老外黑人 | 亚洲精品国产精品国自 | 国产免费一级淫片a级中文 www.avtvtv.com新网址 | 亚洲成人三级在线观看 | 村女艳史理伦一及毛片 | 出差我被公高潮A片久久 | 欧美精品一区二区免费 | 丰满熟妇乱又伦在线无码视频 | 国产乱对白刺激视频户外 | 一级做a爰大片免费 | 亚洲日韩精品一区二区三区无码 | 成人亚洲欧美一区二区三区 | 一本—道久久a久久精品蜜桃 | 99久久久久国产精品免费 |