超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
黑人内谢中国女人视频,四虎永久地址www成人,av第一福利网站
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-mucolipin 1/AP Conjugated antibody (bs-18731R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18731R-AP
英文名稱 Rabbit Anti-mucolipin 1/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的粘脂蛋白1抗體
別    名 MCLN1_HUMAN ; Mcoln 1 ; Mcoln1 ; MG 2 ; MG-2 ; MG2 ; ML 4 ; ML4 ; MLIV ; MST080 ; MSTP080 ; Mucolipidin ; Mucolipin-1 ; Mucolipin1 ; TRP ML1 ; TRPML1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  跨膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, Monkey, Cat, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human mucolipin 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV. [provided by RefSeq, Oct 2009]

Function:
Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis.

Subcellular Location:
Cell membrane. Late endosome membrane. Lysosome membrane.Entrez Gene: 57192 Human Entrez Gene: 94178 Mouse Entrez Gene: 288371 Rat Omim: 605248 Human SwissProt: Q9GZU1 Human SwissProt: Q99J21 Mouse Unigene: 567548 Human Unigene: 631858 Human Unigene: 8356 Mouse

Tissue Specificity:
Widely expressed in adult and fetal tissues.

DISEASE:
Defects in MCOLN1 are the cause of mucolipidosis type IV (MLIV) [MIM:252650]; also known as sialolipidosis. MLIV is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration and strabismus. Storage bodies of lipids and water-soluble substances are seen by electron microscopy in almost every cell type of the patients. Most patients are unable to speak or walk independently and reach a maximal developmental level of 1-2 years. All patients have constitutive achlorhydia associated with a secondary elevation of serum gastrin levels. MLIV may be due to a defect in sorting and/or transport along the late endocytic pathway. MLIV is found at relatively high frequency among Ashkenazi Jews.

Similarity:
Belongs to the transient receptor (TC 1.A.4) family. Polycystin subfamily. MCOLN1 sub-subfamily.

Database links:

Entrez Gene: 57192 Human

Entrez Gene: 94178 Mouse

Entrez Gene: 288371 Rat

Omim: 605248 Human

SwissProt: Q9GZU1 Human

SwissProt: Q99J21 Mouse

Unigene: 567548 Human

Unigene: 631858 Human

Unigene: 8356 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 精品国产在 | 久久国产精99精产国高潮 | 伊人久久久精品区aaa片 | 欧美日韩一区二区三区精品 | 久久双人床双人片 | 草久在线观看 | 中文字幕亚洲乱码 | 水牛影视一区二区三区久 | 久久综合色鬼综合色 | 久久青草网站 | 日韩精品综合网 | 午夜天堂成人欧美www无码 | 强乱中文字幕亚洲精品 | 亚洲AV无码一区东京热 | 97热在线精品视频在线观看 | 曰韩无码二三区中文字幕 | 久久久一牛精品99久久精品66 | 免费一区二区中文字幕 | 亚洲精品四区麻豆文化传媒 | 欧美日韩在线一区二区三区 | 99在线精品视频免费观看20 | 国产探花在线观看视频 | av最新在线观看 | 720lu国产刺激在线观看 | 无码人妻aⅴ一区二区三区鲁大师 | 中文字幕一区二区三区久久 | 亚洲欧美精品SUV | 好男人社区WWW在线观看 | 一级毛片短视频 | 色播久久人人爽人人爽人人片av | 国产一二三区写真福利视频 | 久久亚洲影院 | 麻豆国产在线播放 | 亚洲色欧美在线影院 | 亚洲欧美日本国产 | 一本岛在线视频 | 免费观看的a级毛片的网站 国产精品高清视亚洲精品 波多野结衣乳巨码无在线播放 | 国产精品亚洲综合一区二区三区 | 欧美日韩特级黄片观看 | 欧美精品久久久久久久影视 | av污在线观看 |