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Rabbit Anti-LSM2/C6orf28/APC Conjugated antibody (bs-18427R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18427R-APC
英文名稱 Rabbit Anti-LSM2/C6orf28/APC Conjugated antibody
中文名稱 APC標記的6號染色體開放閱讀框28抗體
別    名 C6orf28; Chromosome 6 open reading frame 28; G7b; LSM 2; Lsm2; LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae); Lsm2 protein; LSM2_HUMAN; OTTHUMP00000029159; Protein G7b; Small nuclear ribonuclear protein D homolog; snRNP; snRNP core Sm like protein Sm x5; snRNP core Sm-like protein Sm-x5; U6 snRNA associated Sm like protein LSm2; U6 snRNA-associated Sm-like protein LSm2; YBL026W.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LSM2/C6orf28
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]

Function:
Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the snRNP Sm proteins family.

Database links:

Entrez Gene: 57819 Human

Entrez Gene: 27756 Mouse

Entrez Gene: 684148 Rat

Omim: 607282 Human

SwissProt: Q9Y333 Human

SwissProt: O35900 Mouse

Unigene: 103106 Human

Unigene: 165735 Mouse

Unigene: 216424 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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