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Rabbit Anti-LSM14A/C19orf13/APC Conjugated antibody (bs-18437R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18437R-APC
英文名稱 Rabbit Anti-LSM14A/C19orf13/APC Conjugated antibody
中文名稱 APC標記的LSM14A蛋白抗體
別    名 AlphaSNBP; C19orf13; Chromosome 19 open reading frame 13; DKFZp434D1335; FAM61A; Family with sequence similarity 61 member A; hRAP55; hRAP55A; LS14A_HUMAN; LSM14 homolog A (SCD6 S cerevisiae); LSM14 homolog A; LSM14A; Protein FAM61A; Protein LSM14 homolog A; Protein SCD6 homolog; Putative alpha synuclein binding protein; Putative alpha-synuclein-binding protein; RAP55; RNA associated protein 55; RNA-associated protein 55A; SCD6 homolog A (S cerevisiae).  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  轉運蛋白  結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, Guinea Pig, Cat, Danio)
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LSM14A/C19orf13
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008]

Function:
Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs.

Subunit:
Component of a ribonucleoprotein (RNP) complex.

Subcellular Location:
Cytoplasm. Cytoplasm > P-body. Targeted to stress granules (SGs) in response to cellular stress.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the LSM14 family.
Contains 1 DFDF domain.

Database links:

Entrez Gene: 26065 Human

Entrez Gene: 67070 Mouse

Entrez Gene: 361554 Rat

Omim: 610677 Human

SwissProt: Q8ND56 Human

SwissProt: Q8K2F8 Mouse

Unigene: 407368 Human

Unigene: 276503 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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