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Rabbit Anti-ZNF289/ARFGAP2/AP Conjugated antibody (bs-18504R-AP)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18504R-AP
英文名稱 Rabbit Anti-ZNF289/ARFGAP2/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的鋅指蛋白289抗體
別    名 ADP-ribosylation factor GTPase-activating protein 2; ARF GAP 2; ARFG2_HUMAN; ARFGAP2; FLJ14576; FLJ26000; GTPase activating protein ZNF289; GTPase-activating protein ZNF289; IRZ; Nbla10535; Zfp289; Zinc finger protein 289; Zinc finger protein 289 ID1 regulated; ZNF 289.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, Sheep, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF289/ARFGAP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
ZNF289 functions as a GTPase-activating protein (GAP) for ARF family proteins. Localizing to the cytoplasmic side of the Golgi apparatus, ZNF289 contains one ARF-GAP domain and is found associated with COP-I-coated vesicles.

Function:
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.

Subunit:
Interacts with the coatomer complex. Interacts with the C-terminal appendage domain of COPG1.

Subcellular Location:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note: Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.

Similarity:
Contains 1 Arf-GAP domain.

Database links:

Entrez Gene: 84364 Human

Entrez Gene: 505438 Cow

Entrez Gene: 77038 Mouse

Entrez Gene: 362162 Rat

Omim: 606908 Human

SwissProt: A1L520 Cow

SwissProt: Q8N6H7 Human

SwissProt: Q99K28 Mouse

SwissProt: Q3MID3 Rat

Unigene: 436204 Human

Unigene: 43636 Mouse

Unigene: 3707 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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