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Rabbit Anti-MEST/RBITC Conjugated antibody (bs-18797R-RBITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18797R-RBITC
英文名稱 Rabbit Anti-MEST/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的中胚層特異性轉錄同源蛋白MEST抗體
別    名 DKFZp686L18234; EC 3.-.-.-; Mesoderm specific transcript (mouse) homolog; Mesoderm specific transcript homolog (mouse); Mesoderm-specific transcript homolog protein; MEST; MEST_HUMAN; MGC111102; MGC8703; OTTHUMP00000210362; OTTHUMP00000210364; OTTHUMP00000210367; Paternally expressed gene 1; Paternally-expressed gene 1 protein; PEG1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  轉錄調節因子  淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MEST
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in hydatidiform moles, but barely expressed in dermoid cysts. Biallelic expression is detected in blood lymphocytes. Seems to imprinted in an isoform-specific manner rather than in a tissue-specific manner in lymphocytes. Isoform 1 is expressed only from the paternal allele. Isoform 2 is expressed from both the paternal allele and the maternal allele.

Similarity:
Belongs to the AB hydrolase superfamily.

Database links:

Entrez Gene: 4232 Human

Entrez Gene: 404180 Cow

Entrez Gene: 607717 Dog

Entrez Gene: 17294 Mouse

Entrez Gene: 100147710 Pig

Entrez Gene: 58827 Rat

Omim: 601029 Human

SwissProt: Q2HJM9 Cow

SwissProt: Q5EB52 Human

SwissProt: Q07646 Mouse

SwissProt: Q6P5P5 Rat

Unigene: 270978 Human

Unigene: 59431 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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