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Rabbit Anti-NDST3/BF488 Conjugated antibody (bs-19064R-BF488)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19064R-BF488
英文名稱 Rabbit Anti-NDST3/BF488 Conjugated antibody
中文名稱 BF488標記的NDST3蛋白抗體
別    名 Bifunctional heparan sulfate N deacetylase/N sulfotransferase 3; Glucosaminyl N deacetylase/N sulfotransferase 3; Glucosaminyl N-deacetylase/N-sulfotransferase 3; Heparan sulfate N-sulfotransferase 3; hNDST 3; hNDST-3; hNDST3; HSST 3; HSST3; MGC130028; MGC130029; N deacetylase/N sulfotransferase (heparan glucosaminyl) 3; N heparan sulfate sulfotransferase 3; N HSST 3; N-heparan sulfate sulfotransferase 3; N-HSST 3; NDST 3; NDST-3; NDST3; NDST3_HUMAN; PRO4998; UNQ2544.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 101kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NDST3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin. [provided by RefSeq, Nov 2008]

Function:
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high deacetylase activity but low sulfotransferase activity.

Subcellular Location:
Golgi apparatus membrane.

Tissue Specificity:
Expressed in brain, kidney, liver, fetal and adult lung, adult pancreas, placenta, fetal spleen and fetal thymus. Not detected in adult/ fetal heart and skeletal muscle.

Similarity:
Belongs to the sulfotransferase 1 family. NDST subfamily.

Database links:

Entrez Gene: 9348 Human

Entrez Gene: 83398 Mouse

Entrez Gene: 295430 Rat

Omim: 603950 Human

SwissProt: O95803 Human

SwissProt: Q9EQH7 Mouse

Unigene: 480596 Human

Unigene: 443908 Mouse

Unigene: 487979 Mouse

Unigene: 228192 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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