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Rabbit Anti-EML2/BF555 Conjugated antibody (bs-20006R-BF555)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-20006R-BF555
英文名稱 Rabbit Anti-EML2/BF555 Conjugated antibody
中文名稱 BF555標記的EML2蛋白抗體
別    名 1600029N02Rik; Echinoderm microtubule associated protein like 2; Echinoderm microtubule-associated protein-like 2; Echinoderm MT associated protein like protein 70; ELP70; EMAL2_HUMAN; EMAP-2; EMAP2; EML2; HuEMAP-2.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  細胞凋亡  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EML2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Microtubules are components of the actin cytoskeleton that play crucial roles in cell morphogenesis, cell motility, spindle formation and chromosome movements. Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules. EML2 (echinoderm microtubule associated protein like 2), also known as ELP70, EMAP2 or EMAPL2, is a cytoplasmic protein that acts to elongate microtubules, while at the same time making them more dynamic. Like other members of the EML family, EML2 contains a hydrophobic ELP (HELP) domain and a large WD repeat domain, both of which allow EML2 to participate in cytoskeleton assembly.

Function:
May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

Subcellular Location:
Cytoplasm; cytoskeleton.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the WD repeat EMAP family.
Contains 11 WD repeats.

Database links:

Entrez Gene: 24139 Human

Entrez Gene: 72205 Mouse

Entrez Gene: 192360 Rat

SwissProt: O95834 Human

SwissProt: Q7TNG5 Mouse

SwissProt: Q6P6T4 Rat

Unigene: 24178 Human

Unigene: 154121 Mouse

Unigene: 76362 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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