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Rabbit Anti-SLC39A14/BF488 Conjugated antibody (bs-19829R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19829R-BF488
英文名稱 Rabbit Anti-SLC39A14/BF488 Conjugated antibody
中文名稱 BF488標記的溶質載體家族蛋白39成員A14抗體
別    名 Cig19; KIAA0062; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; NET34; S39AE_HUMAN; SLC39A14; Solute carrier family 39 (zinc transporter), member 14; Solute carrier family 39 member 14; Zinc transporter ZIP14; ZIP-14; ZIP14; Zrt Irt like protein 14; Zrt- and Irt-like protein 14.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  發育生物學  信號轉導  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Chimpanzee, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC39A14
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]

Function:
May be able to transport iron (By similarity). Acts as a zinc-influx transporter.

Subunit:
Homotrimer.

Subcellular Location:
Cell membrane. Cell projection > lamellipodium. Localized to the plasma membrane and also found colocalized with F-actin concentrated on lamellipodiae.

Tissue Specificity:
Ubiquitously expressed, with increased expression in liver, pancreas, fetal liver, thyroid gland, left and right ventricle, right atrium and fetal heart. Weakly expressed in spleen, thymus, and peripheral blood leukocytes.

Similarity:
Belongs to the ZIP transporter (TC 2.A.5) family.

Database links:

Entrez Gene: 464044 Chimpanzee

Entrez Gene: 23516 Human

Entrez Gene: 100387296 Marmoset (common)

Entrez Gene: 213053 Mouse

Entrez Gene: 100172692 Orangutan

Omim: 608736 Human

SwissProt: Q15043 Human

SwissProt: Q75N73 Mouse

SwissProt: Q5RAB7 Orangutan

Unigene: 491232 Human

Unigene: 270647 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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