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Rabbit Anti-p66 beta/GATAD2B/BF488 Conjugated antibody (bs-21073R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-21073R-BF488
英文名稱 Rabbit Anti-p66 beta/GATAD2B/BF488 Conjugated antibody
中文名稱 BF488標記的p66β蛋白抗體
別    名 C430014D17Rik; FLJ37346; GATA zinc finger domain containing 2B; GATA zinc finger domain containing protein 2B; GATA zinc finger domain-containing protein 2B; GATAD2B; KIAA1150; MGC138257; MGC138285; mKIAA1150; p66/p68; P66B_HUMAN; P66beta; RGD1308533; RP11-216N14.6; transcription repressor p66 beta component of the MeCP1 complex; Transcriptional repressor p66 beta; Transcriptional repressor p66-beta.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 66kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human p66 beta
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a zinc finger protein transcriptional repressor. The encoded protein is part of the methyl-CpG-binding protein-1 complex, which represses gene expression by deacetylating methylated nucleosomes. Mutations in this gene are linked to intellectual disability and dysmorphic features associated with mental retardation. [provided by RefSeq, Jun 2016]

Function:
Has transcriptional repressor activity. Targets MBD3 to discrete loci in the nucleus.

Subcellular Location:
Nucleus. Nuclear, in discrete foci.

Tissue Specificity:
Ubiquitous.

Similarity:
Contains 1 GATA-type zinc finger.

Database links:

Entrez Gene: 57459 Human

Entrez Gene: 229542 Mouse

Entrez Gene: 310614 Rat

SwissProt: Q8WXI9 Human

SwissProt: Q8VHR5 Mouse

Unigene: 4779 Human

Unigene: 596854 Human

Unigene: 270999 Mouse

Unigene: 133230 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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