超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产高清在线精品一区不卡,亚洲一区www,亚洲一级一级一级
Rabbit Anti-RASGRP4/BF594 Conjugated antibody (bs-19731R-BF594)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19731R-BF594
英文名稱 Rabbit Anti-RASGRP4/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的Ras蛋白特異鳥(niǎo)嘌呤核苷酸釋放因子4抗體
別    名 RASGRP-4; GRP4_HUMAN; Guanyl nucleotide releasing protein 4; RAS guanyl releasing protein 4; RAS guanyl-releasing protein 4; RASGRP 4.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 75kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RASGRP4
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

Function:
Functions as a cation- and diacylglycerol (DAG)-regulated nucleotide exchange factor activating Ras through the exchange of bound GDP for GTP. May function in mast cells differentiation.

Subcellular Location:
Cytoplasm. Cell membrane. Recruited to membranes upon activation by DAG.

Tissue Specificity:
Expressed by mast cells and their progenitors (at protein level). Specifically expressed in mononuclear leukocytes. Highly expressed in myeloid cells compared to lymphoid cells. Also detected in heart, skeletal muscle, spleen, liver, placenta and lung. Not detected in brain. Isoform 1 is the major isoform in normal individuals. Isoform 2 is more significantly expressed in a patient with asthma. Isoform 3 is more significantly expressed in a patient with asthma and a mastocytosis patient.

Similarity:
Belongs to the RASGRP family.
Contains 1 EF-hand domain.
Contains 1 N-terminal Ras-GEF domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 Ras-GEF domain.

Database links:

Entrez Gene: 115727 Human

Entrez Gene: 233046 Mouse

Entrez Gene: 170668 Rat

Omim: 607320 Human

SwissProt: Q8TDF6 Human

SwissProt: Q8BTM9 Mouse

SwissProt: Q8R5I4 Rat

Unigene: 130434 Human

Unigene: 465324 Mouse

Unigene: 213071 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 亚洲欧美日韩精品久久亚洲区色播 | 日本少妇ⅹxxhd第一次 | 国产黄色片子 | 在线观看成人网 | 久久久er热这里只有精品2 | 激情四射五月天婷婷 | 成人午夜性a一级毛片免费看 | 国产福利无码一区二区在线 | 国产视频一区二区在线播放 | 亚洲欧洲日产国码高潮 | 香蕉久久av一区二区三区 | 人妻少妇被粗大爽.9797pw | 精品一区二区三区四 | 日韩欧美中文字幕视频 | 欧美日韩国产第一页 | 成年在线网站免费观看无广告 | 成人精品毛片国产亚洲av十九禁 | av国产免费 | 老妇女色视频 | 亚洲色素色无码专区 | 在线毛片片免费观看 | 18高清免费a级毛片av | 疯狂做受XXXX高潮欧美老妇 | 女人天堂在线a在线 | 久久久久福利视频 | 中国一及毛片 | 欧美一码二码三码无码 | BT天堂新版中文在线 | 波多资源在线中文字幕 | 亚洲成A人片在线观看中文无码 | 中国A级毛片免费观看 | 97国产人妻人人爽人人澡 | 粉嫩粉嫩的18在线观看 | 综合欧美亚洲日本少妇 | 中国黄色a级片 | 水牛影视一区二区三区久 | 国产片XXXXA片国语对白 | 美女黄色在线 | 4444亚洲人成无码网在线观看 | 国产伦理在线观看 | 密臀av一区|